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Neuroendocrinology Letters incl. Psychoneuroimmunology & Chronobiology

 

NeuroendocrinologyİLetters
ISSNİ0172ñ780X Copyrightİ©İ1998 NeuroendocrinologyİLetters

NEL Vol. 18 No. 1
Original Article

1998; 18:21-26
pii: NEL180197A05

 

Acute and chronic effects of insulin on the activities of monoamine oxidase and antioxidant enzymes in the rat hypothalamus

by Vukosava Davidovic, Ratko Radojicic, Gordana Cvijic and Sinisa Djurasevic

Institute of Physiology and Biochemistry, Faculty of Biology, Belgrade, Yugoslavia.

Received: February 27, 1996

Abstract

Acute and chronic effects of insulin on the activities of rat hypothalamic monoamine oxidase (MAO - A), superoxide dismutase (CuZnSOD) and catalase were studied. Only chronic insulin treatment increased MAO - A activity in the hypothalamus independent of the dose applied. However, both acute and chronic insulin treatment suppressed the activity of CuZnSOD, but did not change the activity of catalase.

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