Acid: Lipolytic Effect by M. Beskid, J. Jachimowicz, and Z. Obminski
February 15, 1997
Accepted: May 6, 1997
acid is a structural analogue of nicotinic acid. Metabolic activity
of nicotinic acid is lowering the free fatty acids (FFA) level
in serum by phosphodiesterase activation. Our investigations
proved that quinolinic acid significantly increase FFA scrum
concentration applied alone or in combination with propranolol.
It seems that quinolinic acid inhibits phosphodiesterase activity
in adipocytes. That leads to cyclic AMP increase, lipolytic
intensity and growth of FFA serum concentration.