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Neuroendocrinology Letters incl. Psychoneuroimmunology & Chronobiology


ISSNİ0172ñ780X Copyrightİ©İ1997 NeuroendocrinologyİLetters

NEL Vol. 18 No. 4
Original Article

1998; 18:221-229
pii: NEL182397A05


Melatonin, Dehydroepiandrosterone and
RZR/ROR-Ligand CGP 52608
Attenuate the Stress-Induced Gastric Lesion Formation in Rats
by A. Gruszka, J. Kunert-Radek, M. Pawlikowski and
M. Karasek

Received: November 25, 1997
Accepted: December 3, 1997


The effects of melatonin, dehydroepiandrosterone and CGP 52608 (RZR/ROR-ligand), on gastric lesions induced by the immobilization stress were studied in rats. The administration of all studied substances prior to immobilization caused a significant reduction in the severity of lesions in comparison with the control group, exemplified by a decrease in the number of lesions and their length.

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