The immune system is now seen to be closely integrated
with other physiological circuits, such as the central nervous
system (CNS) and the neuroendocrine system. There is also an
increasing amount of evidence that this integrated circuit is
bidirectional and both systems exert a reciprocal effect on
each other. We have always stressed the interdisciplinary
nature of the science where disciplines and sciences such as
medicine, biochemistry, genetics, psychology, human ethology,
etc. meet and undergo a process of "cross-fertilization."
We also have stressed the indivisibility of the somatic and
psychological processes in the indivisible continuum of human
life from its very beginning and the inseparability of
the development and functions of the central nervous system
and the immunological and neuroendocrine processes.
This transdisciplinary and integrative
aspect of sciences and their entree in the twenty-first century
is the true vision for our common efforts. Integration means
also amalgamation, assimilation, blending, combining, incorporation,
unification and harmony. This last mentioned, harmony, should
be stressed and underlined specifically: a harmony between
different views and approaches, between different methods and
methodologies, different theories and practices. In order to
undertake such a challenge, a new scientific theory and a common
language is required, a language that would be understood across
disciplines and would be able to assist in getting beyond semantic
The bridge between the immune system,
neuroendocrinology and the rest of the central nervous system
opens the gateway to more common understanding and acceptance
across the disciplines. It is an umbrella for the endeavor that
unites various scientific fields in their attempt to elucidate
the processes of experience involved from the earliest stages
of human life.
This integration does cross over the
different disciplines and diagnostic systems. It attaches theoretical
and applied fields, basic research and clinical experience throughout
the whole continuity of human life from conception and onwards.
Integrated Psychoimmuno-Neuroendocrinology represents
a unique opportunity for the primary prevention of psychological,
emotional and physical disorders.