a cathedral, it must be seen
from all points of the compass,
and from inside and out, to understand its perfections."
"... it is as if one were viewing, from the portal, an
exquisite Gothic chapel made entirely of crystal, so that
both the facades and interior structures may be seen at a glance."
Mark Epstein: Proust regained 
The introductory quotations to my editorial refer to the work
of Marcel Proust, who according to Graham Greene "was the
greatest novelist of the twentieth century, just as Tolstoy
was in the nineteenth" .
I read the paper by Daniel Mark Epstein in the New Criterion,
Vol. 19, No.2, October 2000, I associated his comments on Proust
masterwork, "A la recherche du temps perdu" with my
views on science, scientific work and their sincere intentions
throughout the whole creative process of the evidence based
of the main characteristics and prerequisites for the Neuroendocrinology
Letters including Psychoneuroimmunology & Chronobiology,
as it will be evident also from this issue of the Journal, is
a stress on the continuing indivisibility between all creative
processes in human life, between science and art as well as
in every single sign and expression of human intrinsic forces
and potential capacities during the whole evolution of humanity
his Guest Editorial, Professor Béla Mess, summarizes
thoughts and experiences as a life-long scientist, suggesting
the comprehensive approach to scientific research, looking at
the entire organism and avoiding the well-known phenomenon of
"not seeing the forest because of the trees".
comprehensive aspect of scientific approach towards life phenomena
as well as the entity and indivisibility of psychological and
physical processes, is evident by Review article by Lissoni
et. al on "Cancer-psychospritual status interactions."
elegant Invited Review "The hypothalamo-neurohypophysial
response to melatonin" by Marlena Juszczak shows from another
angle the interactions between the different neurohormonal mechanisms.
are very happy to introduce in this issue the Oxford Project
to Investigate Memory and Ageing from University Department
of Pharmacology and the Radcliffe Infirmary Trust, Oxford, United
Kingdom, Eva Hogervorst et al, with their Invited Original Article
of the recent research on the level of serum total testosterone
(TT) in cases of Dementia of the Alzheimer's Type (DAT).
five original articles in this issue by highly distinguished
scientists and colleagues, reflect the broad spectrum of the
both basic and clinical research within the modern sciences
of neuroendocrinology, psychoneuroimmunology and chronobiology.
Ludwig Janus, in his analysis of the film "The Matrix"
summarizes the indivisible continuity of the human life from
the prenatal stages, in interaction with the psychosomatic phenomena
of the individual in the society, and the mutual interdependencies
between the individual destiny, its initiation process and between
the society with the framework of rules, controls, boundaries
including the choice of free will.
last, but not least, I would like to announce a fortunate, innovative
step in the Editorial structure of this Journal, namely Professor
Michal Karasek has accepted my invitation to act as a Deputy
Chief Editor. From now on the manuscripts for consideration
for publication in this Journal, can be sent either to the Editor-in-Chief
or to Prof. Michal Karasek, M.D., Ph.D., Laboratory of Electron
Microscopy, Chair of Pathomorphology, Medical University of
Lodz, Czechoslowacka 8/10, 92-216 Lodz, POLAND, tel/fax: +48
42 675 7613. E-mail: firstname.lastname@example.org
1 Daniel Mark Epstein. Proust regained. The New Criterion Vol.
19, No.2, October 2000.
Peter G. Fedor-Freybergh. Editorial: All true life lies in encounter.
Neuroendocrinol Lett 1999; 20:15.