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NEUROENDOCRINOLOGY LETTERS
including Psychoneuroimmunology, Neuro
psychopharmacology,
Reproductive Medicine, Chronobiology
and Human Ethology
ISSN 0172–780X

ZDENEK KLEIN AWARD 2002

RECIPIENTS OF
"ZDENEK KLEIN AWARD FOR HUMAN ETHOLOGY" 2002

The Zdenek Klein Award for Human Ethology 2002
has been granted to:

Jaak Panksepp,
Joseph R. Moskal, Jules B. Panksepp, Roger A. Kroes

For their article entitled
"Comparative Approaches in Evolutionary Psychology: Molecular Neuroscience Meets the Mind"

Neuroevolutionary Psychobiology (Short title)
 [ABSTRACT]     [REFERENCES]      [FULL TEXT PDF]

JAAK PANKSEPP

Born: Tartu, Estonia, June 5, 1943.
Married, 4 Children.

Academic Address:
Dept. of Psychology Bowling Green State Univ. Bowling Green, OH 43403, USA
Email: jpankse@bgnet.bgsu.edu

Jaak Panksepp is Distinguished Research Professor Emeritus of Psychobiology, at Bowling Green State University and Adjunct Professor of Psychiatry at the Medical College of Ohio at Toledo. He is also currently the Head of Affective Neuroscience Research at the Chicago Institute for Neurosurgery and Neuroresearch (Evanston, Illinois).

Jaak Panksepp

Biographical Sketch:

I. EDUCATION (Psychology, Psychobiology and Neuroscience)

B.S. 1965 University of Pittsburgh, Pittsburgh, Pennsylvania
M.S. 1967 University of Massachusetts, Amherst, Massachusetts
Ph.D. 1969 University of Massachusetts, Amherst, Massachusetts
(Dissertation: "The Neural Basis of Aggression")

II. PROFESSIONAL BACKGROUND

1968 - 1969 Instructor; Smith College, Northampton, Massachusetts
1969 - 1970 NSF Post-doctoral research fellow; University of Sussex, Brighton, England
1970 - 1971 NIGMS Post-doctoral research fellow; University of Sussex, Brighton, England
1971 - 1972 NIMH Post-doctoral research fellow; Worcester Foundation for Experimental
Biology, Shrewsbury, Massachusetts
1972 - 1974 Assistant Professor; Bowling Green State University, Bowling Green, OH
1974 - 1977 Associate Professor; BGSU, Bowling Green, OH
1977 - 1988 Professor; BGSU, Bowling Green, OH
1988 - Present Distinguished Research Professor of Psychology, BGSU (Emeritus since 1999)
1999 - 2000 Visiting Professor, Dept. of Psychology, University of Michigan
1990 - Present Adjunct Professor of Psychiatry, Medical College of Ohio at Toledo
2001 - Present Head, Affective Neuroscience Research, Chicago Institute for Neurosurgery and Neuroresearch and Falk Center for Molecular Therapeutics, Adjunct Professor of Psychology, Northwestern University.
2002 - 2003 Honorary Leverhulme Visiting Professor, University of Portsmouth (UK)

III. TEACHING EXPERTISE AND INTERESTS

- Brain Mechanisms of Behavior
- Developmental Psychobiology
- Psychobiology of Emotions and Motivations
- Developmental Brain Research
- Neuroanatomy, Neurophysiology and Neuropsychology
- Clinical Psychopharmacology
- Developmental Disorders
- Abnormal Behavior/Biological Psychiatry
- Experimental Methods
- Affective Neuroscience


IV. SPECIAL HONORS AND AWARDS

- BGSU Special Achievement Award (1974 & 1975)
- BGSU Research and Development Award (1976)
- Sigma Xi Outstanding Young Scientist Award (1977)
- NIMH Research Scientist Development Award (1975 - 1980)
- Award, Meritorious Research in Autism, Toledo Soc. for Autism, 1987
- Outstanding Contributor to Graduate Education at BGSU (1988)
- Distinguished Research Professorship in Psychobiology, BGSU (1988)
- Professional of the Year, NW Ohio Autism Society (1991)
- Member of Interdisciplinary Core Faculty, NIMH Post-doctoral training program for the Study of Emotions (MH-18931), 3 Year appointment, UC Berkeley and USF (1989-1991), 4 year re-appointment (1992-1995), 2 year re-appointment, Univ. of WI (1996-1998)
- Professor of the Year, Psi Chi National Honor Soc., BGSU Chapter (1996-1997)
- Zdenek Klein Award for Human Ethology, year 2002 for contribution to the Special Issue on Human Ethology and Evolutionary Psychology entitled "Comparative Approaches in Evolutionary Psychology: Molecular Neuroscience Meets the Mind" Supplement to the Neuroendocrinology Letters, Vol 23, Dec. 2002.


Jaak Panksepp finished his doctoral studies at the University of Massachusetts in behavioral neuroscience (Ph.D., 1969) working on aggression systems of the brain and then pursued postdoctoral work in feeding and nutrition at the University of Sussex and sleep physiology at the Worcester Foundation for Experimental Biology. His present research is devoted to the analysis of neuroanatomical and neurochemical mechanisms of emotional behaviors (in the emerging field of affective neuroscience), with a focus on understanding how separation responses, social bonding, social play, fear, anticipatory processes, and drug craving are organized in the brain, especially with reference to psychiatric disorders. His past work in hypothalamic mechanisms of energy balance control was supported by a NIMH Research Scientist Development Award. He is author of over 200 scientific articles which deal with basic physiological mechanisms of motivated behavior. He is co-editor of the multi-volume "Handbook of the Hypothalamus" and of "Emotions and Psychopathology." He edited a series on the "Advances in Biological Psychiatry," and his text on Affective Neuroscience: The Foundations of Human and Animal Emotions (Oxford) has helped guide and conceptualize basic emotion research. His general research orientation is that a detailed understanding of basic emotional systems at the neural level will highlight the basic sources of human values and the nature and genesis of emotional disorders in humans. He has helped develop the controversial opioid-antagonist therapy for autistic children based on his pre-clinical investigations into brain circuits which control social behaviors and is pursuing new therapies for the treatment of Attention Deficit/Hyperactivity Disorders (ADHD).

At the present time, Panksepp is among a handful of active investigators who is doing empirical work on the neurobiological nature of emotional processes. His empirical and theoretical work during the past decade have directly touched most of the known brain systems which elaborate the basic emotions. His interests and theoretical contributions will be summarized by noting the review-type papers that he has published during the past two decades (see attached references). Overall perspectives on brain organization of emotionality are summarized in citations 1-6. His contributions to our understanding of basic anticipatory/expectancy mechanisms of the brain which have implications for understanding schizophrenia, as summarized in citations 7-9. He has contributed to our understanding of basic social-emotional mechanisms in the brain and is one of the founders of this field, as reviewed in citations 10-15. He initiated work on our understanding of how play/joy processes are organized in the brain (as reviewed in citations 16-19), and how separation anxiety/fear and other stress processes reflect neural organization (as reviewed in citations 20-23). He has helped integrate our understanding of neurochemical coding of behavior, with a specific focus on basic psycho-behavioral operating systems of the brain in refs 24-26. He has developed a new animal model of depression (ref 36) and has helped translate some of the basic animal work into clinical practice (i.e., naltrexone treatment of autistic disorders, as summarized in refs 27-34) and related psychiatric issues in ref. 35-40. His earlier contributions to the field of energy balance regulation are summarized in citations 41-47. In addition to his academic work, he presently serves as the director of the non-profit Memorial Foundation for Lost Children which provides information and advice to parents concerning various childhood neuropsychiatric disorders, especially autism and ADHD.

REFERENCES

The following reviews are general contributions to the neuro-theoretical understanding of emotions

1. Panksepp, J. (1982). Toward a general psychobiological theory of emotions. The Behavioral and Brain Sciences, 5, 407-467.

2. Panksepp, J. (1985). Mood changes: In Handbook of Clinical Neurology. Vol. 1. (45): Clinical Neuropsychology. pp. 271-285, Amsterdam, Elsevier Science Publishers.

3. Panksepp, J. (1989). The neurobiology of emotions: Of animal brains and human feelings. In T. Manstead & H. Wagner (Eds.) Handbook of Psychophysiology, pp 5-26, Chichester, UK: John Wiley & Sons.

4. Panksepp, J. (1991). Affective Neuroscience: A conceptual framework for the neurobiological study of emotions. In International Reviews of Emotion Research, (K. Strongman, Ed.) pp 59-99, Chichester, UK: Wiley.

5. Panksepp (1995) Affective Neuroscience: A paradigm to study the animate circuits for human emotions. In. Emotions: An Interdisciplinary Approach, pp 29-60, Hillsdale, NJ: Erlbaum.

6. Panksepp, J. & Miller, A. (1996), Emotions and the aging brain. Regrets and remedies, In eds. C. Magai & S.H. McFadden, Handbook of Emotion, Adult Development and Aging, (San Diego, Academic Press), pp. 3-26.

The following references are to ancipatory/expectancy mechanisms of the brain.

7. Panksepp, J. (1981). Hypothalamic integration of behavior: Rewards, punishments, and related psycho- biological process. In Handbook of the Hypothalamus, vol. 3, Part A. Behavioral Studies of the Hypothalamus. P. J. Morgane and J. Panksepp (Eds.). pp. 289-487, New York: Marcel Dekker.

8. Panksepp, J. (1986, ). The anatomy of emotions. In Emotion: Theory, Research and Experience Vol. III. Biological Foundations of Emotions. R. Plutchik (Ed.). pp. 91-124, New York: Academic Press.

9. Panksepp, J. (1992). A critical role for "Affective Neuroscience" in resolving what is basic about basic emotions. Psychological Review, 99, 554-560.

The following references are to our work on separation-distress and attachment processes of the brain.

10. Panksepp, J. , Herman, B. H. , Villberg, T. , Bishop, P. and DeEskinazi, F. G. (1980). Endogenous opioids and social behavior. Neuroscience and Biobehavioral Reviews, 4, 473-487.

11. Panksepp, J. (1981). Brain opioids: A neurochemical substrate for narcotic and social dependence. In Progress in theory in psychopharmacology. S. Cooper (Ed.). pp. 149-175, London: Academic Press.

12. Panksepp, J. , Siviy, S. M. , & Normansell, L.A. (1985). Brain opioids and social emotions. In M. Reite and T. Fields (eds) The Psychobiology of Attachment and Separation, pp. 3-49, NY, Academic Press.

13. Panksepp, J. , Normansell, L. , Herman, B. , Bishop, P. & Crepeau, L. (1988). Neural and neurochemical control of the separation distress call. In. J. D. Newman (Ed.). The Physiological Control of Mammalian Vocalizations. pp 263-300, New York: Plenum Press.

14. Panksepp, J. (1988). Brain opioids and social affect. Advances in Thanatology, 6, 59-65.

15. Panksepp, J., Newman, J.D., & Insel, T.R. (1992). Critical conceptual issues in the analysis of separation distress systems of the brain. In. (K.T. Strongman, ed) International Review of Studies on Emotion, Vol. 2, pp. 51-72, Chichester, UK: John Wiley & Sons.

The following references summarize our work on the psychobiological substrates of play.

16. Panksepp, J. , Siviy, S. , & Normansell, L. (1984). The psychobiology of play: Theoretical and methodological perspectives. Neuroscience and Biobehavioral Reviews, 8, 465-492.

17. Panksepp, J. (1986). The psychobiology of prosocial behaviors: separation distress, play, and altruism. In C. Zahn-Waxler, E. M. Cummings & R. Iannotti (Eds.). Altruism and Aggression, Biological and Social Origins. pp. 19-57, Cambridge, Cambridge University Press.

18. Panksepp, J., Normansell, L., Cox, J. , Crepeau, L. and Sacks, D.S. (1987). Psychopharmacology of social play. In. J. Mos (Ed.) Ethnopharmacology of Social Behavior, pp. 132-144, Dordrecht: Martinus Nijhoff.

19. Panksepp, J. (1993). Rough and tumble play: A fundamental brain process. In. K. MacDonald (ed.) Parent-Child Play. pp. 147-184, Albany, NY: SUNY Press.

The following references summarize our work on fear/anxiety/stress systems in brain.

20. Panksepp, J. (1990). The psychoneurology of fear: Evolutionary perspectives and the role of animal models in understanding human anxiety. In: Handbook of Anxiety. pp. 3-58, Amsteram: Elsevier.

21. Panksepp, J., Sacks, D.S., Crepeau, L.J., Abbott, B.B. (1991). The psycho- and neuro-biology of fear systems in the brain. In Aversive Events and Behavior, M.R. Denny (Ed.), pp. 7-59, Hillsdale, NJ: Lawrence Erlbaum.

22. Panksepp, J. (1990). A role for "affective neuroscience" in understanding stress: The case of separation distress circuitry. Psychobiology of Stress, A. Oliverio (Ed.) Advanced NATO Workshop Series, pp. 41-58, Dordrecht: Kluwer.

23. Panksepp, J. (1996) Modern approaches to understanding fear: From laboratory to clinical practice. Advances in Biological Psychiatry, Vol. 2, pp 209-230, JAI Press Inc, Greenwich CT.

The following summarize some of our thinking on neurochemical coding of emotions.

24. Panksepp, J. (1986). The neurochemistry of behavior. Annual Review of Psychology, 37, 77-107.

25. Panksepp, J. (1992). Oxytocin effects on emotional processes: Separation distress, social bonding, and relations to psychiatric disorders. Annals of the New York Academy of Sciences, v. 652, pp. 243-252.

26. Panksepp, J. (1993). Neurochemical control of moods and emotions: Amino acids to neuropeptides. In. M. Lewis and J. Haviland (Eds.) The Handbook of Emotions. pp. pp 87-107, New York: Guilford.

The following summarize our work on brain socio-emotional systems and autism.

27. Panksepp, J. (1979). A neurochemical theory of autism. Trends in Neuroscience, 2, 174-177.

28. Panksepp, J. , & Sahley, T. (1987). Possible brain opioid involvement in disrupted social intent and language development of autism. In E. Schopler & G. Mesibov (Eds.). Neurobiological Issues in Autism. pp. 357-382, New York: Plenum Press.

29. Panksepp, J. and Lensing, P. (1991). A synopsis of an open-trial of naltrexone treatment of autism with four children. Journal of Autism and Developmental Disorders, 21, 243-249.

30. Panksepp, J., Lensing, P., Leboyer, M., and Bouvard, M.P. (1991). Naltrexone and other potential new pharmacological treatments of autism. Brain Dysfunction, 4, 281-300.

31. Leboyer, M., Bouvard, M.P., Launay, J.-M., Tabuteau, F., Waller, D., Dugas, M., Kerdelhue, B., Lensing, P. and Panksepp, J. (1992). A double-blind study of naltrexone in infantile autism. Journal of Autism and Developmental Disorders. 22, 311-321.

32. Bouvard, M.P., Leboyer, M., Launay, J.-M., Recasens, C., Plumet, M.-H., Waller-Perotte, W., Tabuteau, F., bondoux, D., Dugas, M., Lensing, P. & Panksepp, J. (1995). Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study. Psychiatry Research, 58, 191-201.

33. McBride, J.A. & Panksepp, J. (1995). An examination of the phenomenology and the relaibility of ratings of compulsive behavior in autism. Journal of Autism and Developmental Disorders, 25, 381-395.

34. Lensing, P., Schimke, H., Klimesch, W., Pap, V., Szemes, G., Klingler, D. & Panksepp, J., (1995). Clinical case report: opiate antagonist and event-releated desynchronization in 2 autistic boys. Neuropsychobiology, 32, 16-23.

The following are related to other aspects of emotions and psychiatric issues.

35. Panksepp, J. (1989). The psychobiology of emotions: The animal side of human feelings. In G. Gainotti & C. Caltagirone (Eds). Emotions and the dual brain: Experimental Brain Research Series 18, pp. 31-55, Berlin: Springer-Verlag.

36. Panksepp, J. (1988). Brain Emotional Circuits and Psychopathologies, In M. Clynes and J. Panksepp (Eds.) Emotions and Psychopathology, pp. 37-76, New York, Plenum Press.

37. Panksepp, J. , Yates, G., Ikemoto, S., & Nelson, E. (1991). Simple ethological models of depression: Social- isolation induced "despair" in chicks and mice. In. B. Olivier, J. Mos., J.L. Slangen (Eds.) Animal Models in Psychopharmacology, pp. 161-181, Basel: Birkhauser.

38. Panksepp, J., Newman, J.D. and Insel, T.R. (1992). Critical conceptual issues in the analysis of separation-distress systems of the brain. In K.T. Strongman (ed.) International Review of Studies on Emotions. pp. 51-72, John Wiley and Sons, Ltd.

39. Panksepp, J. (1995) The emotional brain and biological psychiatry, In Advances in biological psychiatry, (J. Panksepp, ed), pp. 263-286, Greenwich, CT: JAI Press.

40. Panksepp, J. (1998). Attention deficit hyperactivity disorders, psychostimulants, and inteolerance of childhood playfulness: a tragedy in the making? Current Directions in Psychological Sciences, 7: 91-98.

Older reviews of work on energy balance regulation in the body.

41. Panksepp, J. (1974). Hypothalamic regulation of energy balance and feeding behavior. Federation Proceedings 33, 1150-1165.

42. Panksepp, J. (1975). Central metabolic and humoral factors involved in the neural regulation of feeding. Pharmacology Biochemistry and Behavior, Vol. 3, supplement 1, 107-119.

43. Panksepp, J. (1975). Hormonal control of feeding behavior and energy balance. In Hormonal Correlates of Behavior. Vol. 2, An Organismic View. B.E. Eleftheriou & R.L. Sprott (Eds.) pp. 657-695, New York, Plenum Press.

44. Panksepp, J. (1976). On the nature of feeding patterns. In Hunger: Basic Mechanisms and Clinical Implications. D. Novin, W. Wyrwicka & G. Bray (eds.) pp. 369-382, New York, Raven Press.

45. Panksepp, J. and Meeker, R.B. (1977). Effects of insulin and hypothalamic lesions of glucose preference in rats. In. Food Intake and Chemical Senses. Y. Katsuki (ed). pp. 343-356, Tokyo: Univ. of Tokyo Press.

46. Panksepp, J. (1978). Feeding patterns: Data reduction and theoretical considerations. In Hunger Models: Quantitative Theory of Feeding Control. D. Booth (ed). pp 143-166, London: Academic Press.

47. Panksepp, J., Bishop, P. & Rossi, J. (1979). Neurohumoral and endocrine control of feeding. Psychoneuroendocrinology, 4, 89-106.

 

NEUROENDOCRINOLOGY LETTERS
including Psychoneuroimmunology, Neuro
psychopharmacology,
Reproductive Medicine, Chronobiology
and Human Ethology
ISSN 0172–780X


A peer-reviewed transdisciplinary Journal covering Neuroendocrinology, Psychoneuroimmunology, Neuropsychopharmacology, Reproductive Medicine, Chronobiology and Human Ethology for RAPID publication of Original Papers, Review Articles, State-of-the-Art, Clinical Reports, Meta-Analyses and other contributions from all the fields covered by Neuroendocrinology Letters. E-mail: info@nel.edu

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