Vol. 29 (6) 2008 Neuro endocrinology letters

Dipeptide "alaptide" prevented impairments in spontaneous behavior produced with trimethyltin in male rats.

OBJECTIVES: On the animal model of trimethyltin (TMT) induced behavioral deficits the effect of chronic treatment with spirocyclic dipeptide cyclo/alanyl-l-amino-l-cyclopentane-carbonyl (alaptide, AL) was evaluated in adult male rats.

METHODS: Changes in the spontaneous behavioral repertoire were investigated in .....