Vol. 30 (2) 2009 Neuro endocrinology letters

Effects of fulvestrant, an estrogen receptor antagonist, on MMQ cells and its mechanism.

OBJECTIVES: Unlike the successful endocrine therapy of breast cancers and other estrogen-dependent diseases, little is known about the effect of anti-estrogen treatment on pituitary tumors. Our objectives were to study the effect of fulvestrant, a new type anti-estrogen devoid of any agonistic activities, on prolactinoma cell line MMQ i.....