Type and distribution of indomethacin-induced lesions in the gastrointestinal tract of rat.
OBJECTIVES: The therapy with non-steroidal anti-inflammatory drugs (e.g. indomethacin) is often accompanied with adverse effects in gastrointestinal tract. Aim of this experimental study was to define the time range of the creation of indomethacin-induced gastrointestinal lesions in rat (for prospective study of potential probiotic ther.....