Notice: session_start(): ps_files_cleanup_dir: opendir(/var/lib/php/sessions) failed: Permission denied (13) in /data/www/nel.edu/www/index.php on line 14 Neuro Enocrinology Letters - issue Vol.36(2) 2015 - NeL.edu

Vol. 36 (2) 2015 Neuro endocrinology letters

Alternative splicing of placental lactogen (CSH2) in somatotroph pituitary adenomas.

OBJECTIVES: Somatotroph adenomas secrete supraphysiological amounts of GH, causing acromegaly. We have previously shown epithelial splicing regulator 1 (ESRP1) to play a role in epithelial mesenchymal transition (EMT) progression in these adenomas and account for poor treatment response. We evaluated if the mRNA levels of the GH/CSH ge.....