Articles by author - Eva Anzenbacherova

Effect of dihydromyricetin on benzo[a]pyrene activation in rats.

Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M.

Journal Article 2014; 35(Suppl 2): 158-168 PubMed PMID: 25638381  Keywords:  Animals, Benzo(a)pyrene:administration & dosage, Carcinogens:administration & dosage, DNA Adducts:administration & dosage, Flavonols:administration & dosage, Male, Rats, Rats, Wistar,.    Citation

OBJECTIVES: Flavanol dihydromyricetin (DHM) has been shown to counteract acute ethanol (EtOH) intoxication and reduce excessive E.....

Read abstract  Full text PDF

The influence of rosuvastatin on liver microsomal CYP2C6 in hereditary hypertriglyceridemic rat.

Vecera R, Zacharová A, Siller M, Matuskova Z, Skottová N, Anzenbacherová E, Anzenbacher P.

Journal Article 2012; 33(Suppl 3): 48-52 PubMed PMID: 23353843  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:antagonists & inhibitors, Cholesterol, Dietary:pharmacology, Cytochrome P-450 CYP2C9, Cytochrome P450 Family 2, Fluorobenzenes:pharmacology, Gene Expression Regulation, Enzymologic:drug effects, Humans, Hydroxymethyl.    Citation

OBJECTIVES: The aim of this study was to investigate whether rosuvastatin affects expression and activity of rat CYP2C6. This cytochrome P.....

Read abstract  Full text PDF

Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats.

Matuskova Z, Siller M, Tunkova A, Anzenbacherova E, Zacharova A, Tlaskalova-Hogenova H, Zidek Z, Anzenbacher P.

Evaluation Studies 2011; 32(Suppl 1): 8-14 PubMed PMID: 22167211  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:genetics, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP2E1:genetics, Cytochrome P-450 CYP3A:genetics, Cytochrome P-450 Enzyme System:genetics, Cytochrome P450 Family 2, Cytochromes:genetics, Enzyme Activation:drug ef.    Citation

OBJECTIVES: The aim of the study was to find whether probiotic Lactobacillus casei influences the expression or the activity of cytochrome.....

Read abstract  Full text PDF

Effects of probiotic Escherichia coli Nissle 1917 on expression of cytochromes P450 along the gastrointestinal tract of male rats.

Matuskova Z, Tunkova A, Anzenbacherova E, Vecera R, Siller M, Tlaskalova-Hogenova H, Zidek Z, Anzenbacher P.

Journal Article 2010; 31(Suppl 2): 46-50 PubMed PMID: 21187832  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Colon:enzymology, Cytochrome P-450 CYP3A:metabolism, Cytochrome P-450 Enzyme System:metabolism, Duodenum:enzymology, Escherichia coli, Gastrointestinal Tract:enzymology, Male, Models, Animal, Probiotics:p.    Citation

OBJECTIVES: The aim of the study was to find whether probiotic Escherichia coli Nissle 1917 O6:K5:H1 (EcN) influences the expression of cy.....

Read abstract  Full text PDF

Influence of probiotics on rat liver biotransformation enzymes.

Matuskova Z, Tunkova A, Anzenbacherova E, Zidek Z, Tlaskalova-Hogenova H, Anzenbacher P.

Journal Article 2009; 30(Suppl 1): 41-45 PubMed PMID: 20027143  Keywords:  Animals, Blotting, Western, Cytochrome P-450 Enzyme System:metabolism, Female, Lipopolysaccharides:metabolism, Liver:enzymology, Probiotics:metabolism, Rats, Rats, Wistar, Time Factors,.    Citation

OBJECTIVES: The aim of the study was to find, whether probiotic Escherichia coli Nissle 1917 O6:K5:H1 (EcN) influence the amount and activ.....

Read abstract  Full text PDF

Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system.

Matal J, Matuskova Z, Tunkova A, Anzenbacherova E, Anzenbacher P.

Journal Article 2009; 30(Suppl 1): 36-40 PubMed PMID: 20027142  Keywords:  Animals, Cytochrome P-450 CYP1A2:metabolism, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2E1:metabolism, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System:metabolism, Humans, Indoles:metabol.    Citation

OBJECTIVES: To study the contribution of individual purified porcine CYP1A2, 2E1 and 2A19 enzymes to the biotransformation of skatole.

Read abstract  Full text PDF