Borek-Dohalska L, Klusonova Z, Holecova J, Martinkova M, Barta F, Dracinska H, Cajthaml T, Stiborova M.
Journal Article 2016; 37(Suppl 1): 84-94 PubMed PMID: 28263535 Keywords: Animals, Benzo(a)pyrene:pharmacology, Cytochrome P-450 Enzyme System:metabolism, Endocrine Disruptors:pharmacology, Estradiol:pharmacology, Estrogens:pharmacology, Ethinyl Estradiol:pharmacology, Male, Microsomes, Liver:metabolism, Rats, Rats, Wistar,. CitationOBJECTIVES: The term "endocrine disruptor" (ED) is used for compounds that mimic or antagonize the effects of endogenous hormones. Synthet.....
Borek-Dohalska L, Klusonova Z, Holecova J, Martinkova M, Barta F, Dracinska H, Cajthaml T, Stiborova M. Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their metabolism. Neuro Endocrinol Lett. 2016 Dec; 37(Suppl 1): 84-94
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M.
Journal Article 2015; 36(Suppl 1): 5-12 PubMed PMID: 26757108 Keywords: Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 CYP3A:metabolism, Cytochrome P-450 Enzyme System:metabolism, Cytochrome P450 Family 2, Ethinyl Estradiol:metaboli. CitationOBJECTIVES: 17α-Ethinylestradiol (EE2) is an endocrine disruptor that is an ingredient of oral contraceptives. Here, EE2 metabolism catal.....
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M. A study on 17alpha-ethinylestradiol metabolism in rat and Pleurotus ostreatus. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 5-12
Stiborova M, Cechova T, Borek-Dohalska L, Moserova M, Frei E, Schmeiser H, Paca J, Arlt V.
Journal Article 2012; 33(Suppl 3): 8-15 PubMed PMID: 23353838 Keywords: Aerobiosis:physiology, Air Pollutants:pharmacokinetics, Anaerobiosis:physiology, Animals, Benz(a)Anthracenes:pharmacokinetics, Carcinogens:pharmacokinetics, Cytochrome P-450 Enzyme System:metabolism, Cytochrome-B(5) Reductase:genetics, DNA Adducts:metabol. CitationOBJECTIVES: 2-Nitrobenzanthrone (2-NBA) has recently been detected in ambient air particulate matter. Its isomer 3-nitrobenzanthrone (3-NB.....
Stiborova M, Cechova T, Borek-Dohalska L, Moserova M, Frei E, Schmeiser H, Paca J, Arlt V. Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes. Neuro Endocrinol Lett. 2012 Jan; 33(Suppl 3): 8-15