Articles by author - Iva Macova

Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450.

Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M.

Journal Article 2015; 36(Suppl 1): 38-45 PubMed PMID: 26757124  Keywords:  Animals, Antibodies:immunology, Antibody Formation, Blotting, Western, Cell Line, Tumor, Chickens, Cytochrome P-450 Enzyme System:immunology, Cytochrome P450 Family 2, Eggs, Electrophoresis, Gel, Two-Dimensional, Enzyme-Linked Immunosorbent Assay, Humans,.    Citation

OBJECTIVES: Cytochromes P450 (CYP) are monooxygenases, which metabolize mostly hydrophobic endogenous and exogenous compounds. CYPs withou.....

Read abstract  Full text PDF

Effects of subchronic exposure to simazine on zebrafish (Danio rerio).

Plhalova L, Haluzova I, Macova S, Dolezelova P, Praskova E, Marsalek P, Skoric M, Svobodova Z, Pistekova V, Bedanova I.

Evaluation Studies 2011; 32(Suppl 1): 89-94 PubMed PMID: 22167213  Keywords:  Animals, Behavior, Animal:drug effects, Dose-Response Relationship, Drug, Environmental Exposure, Hepatocytes:drug effects, Herbicides:pharmacology, Kidney:drug effects, Simazine:pharmacology, Survival Analysis, Toxicity Tests, Subchronic:statistics & num.    Citation

OBJECTIVES: Simazine is a triazine herbicide which has been used for a long period in agriculture and in the aquatic environment for contr.....

Read abstract  Full text PDF

Comparison of acute toxicity of ketoprofen to juvenile and embryonic stages of Danio rerio.

Praskova E, Voslarova E, Siroka Z, Macova S, Plhalova L, Bedanova I, Marsalek P, Pistekova V, Svobodova Z.

Comparative Study 2011; 32(Suppl 1): 117-120 PubMed PMID: 22167210  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal:adverse effects, Cell Membrane Permeability:drug effects, Cyclooxygenase Inhibitors:adverse effects, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Embryo, Nonmammalian, Ketoprofen:adverse .    Citation

OBJECTIVES: Ketoprofen is a common human medicine from a class of non-steroidal anti-inflammatory drugs (NSAIDs), which is provably detect.....

Read abstract  Full text PDF

Comparison of the sensitivity of different fish species to medical substances.

Dolezelova P, Macova S, Plhalova L, Pistekova V, Svobodova Z, Bedanova I, Voslarova E.

Comparative Study 2009; 30(Suppl 1): 248-252 PubMed PMID: 20027179  Keywords:  Animals, Disinfectants:administration & dosage, Dose-Response Relationship, Drug, Formaldehyde:administration & dosage, Poecilia, Potassium Permanganate:administration & dosage, Sodium Chloride:administration & dosage, Species Specificity, Time Factors, T.    Citation

OBJECTIVES: Formaldehyde, sodium chloride and potassium permanganate belong to the commonly used substances for fish treatment. The aim is.....

Read abstract  Full text PDF

Terbutryn toxicity to Danio rerio: effects of subchronic exposure on fish growth.

Plhalova L, Macova S, Haluzova I, Slaninova A, Dolezelova P, Marsalek P, Pistekova V, Bedanova I, Voslarova E, Svobodova Z.

Journal Article 2009; 30(Suppl 1): 242-247 PubMed PMID: 20027178  Keywords:  Animals, Body Size:drug effects, Body Weight:drug effects, Czech Republic, Dose-Response Relationship, Drug, Herbicides:administration & dosage, Kidney:drug effects, Rivers, Toxicity Tests, Triazines:administration & dosage, Water Pollutants:administratio.    Citation

OBJECTIVES: The aim of this study was to investigate effects of subchronic exposure to sublethal levels of terbutryn on growth and on hist.....

Read abstract  Full text PDF

Polyaluminium chloride (PAX-18) - acute toxicity and toxicity for early development stages of common carp (Cyprinus carpio).

Macova S, Machova J, Prokes M, Plhalova L, Siroka Z, Dleskova K, Dolezelova P, Svobodova Z.

Journal Article 2009; 30(Suppl 1): 192-198 PubMed PMID: 20027170  Keywords:  Aluminum Hydroxide:administration & dosage, Animals, Anti-Bacterial Agents:toxicity, Carps:embryology, Dose-Response Relationship, Drug, Polymers:administration & dosage,.    Citation

OBJECTIVES: The aim of this study is to assess the toxicity of PAX-18 in different developmental stages of common carp (Cyprinus carpio). .....

Read abstract  Full text PDF