Articles by author - Iveta Mrizova

Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine.

Sulc M, Mrizova I, Cerna T, Frei E, Eckschlager T, Adam V, Kopeckova K, Stiborova M.

Journal Article 2016; 37(Suppl 1): 95-102 PubMed PMID: 28263536 Keywords: Antineoplastic Agents, Phytogenic:metabolism, Cytochrome P-450 CYP3A:metabolism, DNA Adducts:metabolism, Ellipticines:metabolism, Humans, Liposomes, Microsomes,.

OBJECTIVES: Ellipticine is an anticancer agent that functions through multiple mechanisms participating in cell cycle arrest and .....

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Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450.

Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M.

Journal Article 2015; 36(Suppl 1): 38-45 PubMed PMID: 26757124 Keywords: Animals, Antibodies:immunology, Antibody Formation, Blotting, Western, Cell Line, Tumor, Chickens, Cytochrome P-450 Enzyme System:immunology, Cytochrome P450 Family 2, Eggs, Electrophoresis, Gel, Two-Dimensional, Enzyme-Linked Immunosorbent Assay, Humans,.

OBJECTIVES: Cytochromes P450 (CYP) are monooxygenases, which metabolize mostly hydrophobic endogenous and exogenous compounds. CYPs withou.....

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