Relationship of ketamine's antidepressant and psychotomimetic effects in unipolar depression.

Journal Article 2013; 34(4): 287-293 PubMed PMID: 23803871 Keywords: Adult, Antidepressive Agents:therapeutic use, Cross-Over Studies, Depressive Disorder, Major:drug therapy, Double-Blind Method, Female, Hallucinogens:therapeutic use, Humans, Infusions, Intravenous, Ketamine:therapeutic use, Male, Middle Aged, Receptors, .

OBJECTIVES: Ketamine and other NMDA (N-methyl-D-aspartate) antagonists produce fast-acting antidepressant-like effects, although the under.....

The influence of clonidine on oral ketamine-midazolam premedication in intellectually disabled patients indicated for dental procedures: double-blind comparison of two sedation regimes.

Clinical Trial 2012; 33(4): 380-384 PubMed PMID: 22936266 Keywords: Adult, Anesthesia, Dental:methods, Clinical Protocols, Clonidine:administration & dosage, Dental Care for Disabled:methods, Disabled Persons, Dose-Response Relationship, Drug, Double-Blind Method, Drug Combinations, Drug Therapy, Combination:methods, Fema.

BACKGROUND: Dental procedures on intellectually disabled patients represent a clinical challenge. The oral administration of sedating drug.....

Journal Article 2007; 28(6): 781-788 PubMed PMID: 18063949 Keywords: Analysis of Variance, Animals, Behavior, Animal:drug effects, Dose-Response Relationship, Drug, Exploratory Behavior:drug effects, Female, Hallucinogens:pharmacology, Male, Motor Activity:drug effects, N-Methyl-3,4-methylenedioxyamphetamine:pharmacology, .

: 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is a widely abused drug that impairs behavioral, emotional and cognitive functions in .....

Controlled Clinical Trial 2006; 27(5): 587-594 PubMed PMID: 17159818 Keywords: Adolescent, Adult, Basal Metabolism, Brain:metabolism, Brain Mapping, Female, Fluorodeoxyglucose F18:metabolism, Frontal Lobe:metabolism, Humans, Male, Middle Aged, Positron-Emission Tomography:methods, Psychomotor Performance, Schizophrenia:metabolism, T.

OBJECTIVES: With the aim to indicate the functional anatomical substrate of cognitive dysfunction in schizophrenia we evaluated the relati.....