Vol. 20 (1-2) 1999 Neuro endocrinology letters

Progesterone inhibits embryotoxic effect of the complement system.

: The complement system of normal human serum (NHS) manifests a strong, dose dependent embryotoxic potential when administered to chick embryos inducing, among others, also malformations of the brain. We have demonstrated, however, that the degree of complement-induced embryotoxicity varied remarkably in the course of the menstrual cycl.....