Vol. 21 (1) 2000 Neuro endocrinology letters

Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease.

: OBJECTIVES: A retrospective study on the efficacy of melatonin in treatment of sleep and cognitive disorders of Alzheimer's disease was conducted. METHODS: Fourteen patients (8 females, 6 males), mean +/- S.D. age 72 +/- 9 years were included. All patients received 9 mg gelatin melatonin capsules p.o. daily at bedtime for 22 to 35 mon.....