In vitro effect of melatonin on oxygen consumption in liver mitochondria of rats.
OBJECTIVE: To examine the in vitro effect of melatonin on rat mitochondrial liver respiration.
METHODS: Oxygen consumption by liver mitochondria was measured polarographically in the presence of one of the following Krebs' cycle substrates: Lsuccinate, DL-3- beta-hydroxybutyrate or L-malate. Respiratory velocitie.....