Vol. 25 (4) 2004 Neuro endocrinology letters

Isoproterenol-stimulated melatonin production by perifused rat pineal glands: age- and time-related effects.

OBJECTIVES: The purpose of this study was to investigate and compare the effects of the beta-adrenergic agonist, isoproterenol, on induced increase in melatonin production in the pineal gland of young and old rats, at different circadian stages.

MATERIALS AND METHODS: We report here the effects of 10(-6) M isopro.....