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Vol. 27 (3) 2006 Neuro endocrinology letters

Stimulation of the hippocampal glutamate receptor systems induces stress-like responses.

OBJECTIVE: The hypothalamic-pituitary-adrenal (HPA) axis controls glucocorticoid secretion and is in turn controlled by a diverse set of afferents in the brain. However, the precise mechanisms underlying these actions remain to be elucidated. In our previous study, a lesion in the entorhinal cortex, which is the major provider of glutam.....