Vol. 27 (5) 2006 Neuro endocrinology letters

Effect of propylthiouracil on the level of Schiff's bases in tissues of rats on diet with different doses of potassium iodide.

OBJECTIVES: Iodide administration to animals, living in iodine-deficient areas, can induce oxidative processes in the thyroid gland and increase concentration of lipid peroxidation (LPO). Propylthiouracil (PTU)--a well-known antithyroid drug--may also act as an antioxidant. There are some reports, which consider the protective ability o.....