Vol. 28 (1) 2007 Neuro endocrinology letters

Effect of fluoxetine on circadian rhythm of melatonin in patients with major depressive disorder.

OBJECTIVES: The purpose of this study is to explore the response of melatonin circadian rhythm to fluoxetine treatment and its relationship with clinical therapeutic effect.

METHODS: This study investigated salivary melatonin in 13 outpatients with major depressive disorder and age- and sex-matched healthy contro.....