Vol. 28 (5) 2007 Neuro endocrinology letters

Effect of oral glucose on acylated and total ghrelin secretion in acromegalic patients.

OBJECTIVE: The pathophysiology of ghrelin secretion in acromegaly is unclear. Our aim was to study circulating fasting ghrelin levels and their response to oral glucose in acromegalic patients and normal control subjects.

DESIGN AND PATIENTS: 9 acromegalic patients (4 male, 5 female; 59.4+/-3.6 years; 28.6+/-1.0 .....