Vol. 31 (1) 2010 Neuro endocrinology letters

Centrally administered ascorbic acid induces antidiuresis, natriuresis and neurohypophyseal hormone release in rats.

OBJECTIVE: Ascorbic acid represents one of the most important antioxidants and neuromodulators, and plays an important role in the cerebral system. In the present study, we investigated the central effect of ascorbic acid on fluid regulation and electrolyte homeostasis.

METHODS: Male Wistar rats were implanted wi.....