Vol. 34 (6) 2013 Neuro endocrinology letters

Interaction between polyamidoamine (PAMAM) dendrimers and bovine insulin.

OBJECTIVE: In this study the mechanism of interactions between polyamidoamine (PAMAM) dendrimers and bovine insulin was examined. The insulin is a 51 amino acid peptide-hormone involved in the homeostasis of blood glucose levels. This molecule consists of two chains - A and B - linked by two disulphide bridges. As insulin contains four .....