Vol. 37 (7) 2016 Neuro endocrinology letters

Dopamine receptors modulate T lymphocytes via inhibition of cAMP-CREB signaling pathway.

OBJECTIVES: We have previously reported that dopamine D2-like receptors including D2, D3 and D4 receptors are more important in mediating modulation of T cells than dopamine D1-like receptors (D1 and D5 receptors). Here we aimed to clarify the role of D2-like receptors in regulation of differentiation and function of T lymphocyte subset.....