Vol. 40 (1) 2019 Neuro endocrinology letters

Fasting serum leptin levels in elderly women with major depressive disorder: a case-control study.

OBJECTIVE: Leptin is produced in the adipose tissue. It controls energy homeostasis by reducing food intake and increasing energy expenditure. According to the "leptin hypothesis of depression", chronic stress leads to reduced leptin concentration and leptin insufficiency may underlie depressive symptoms. However, it is also hy.....