Demonstration of additivity failure in human circadian phototransduction. Figueiro M, Bullough J, Bierman A, Rea M. Clinical Trial 2005; 26(5): 493-498 PubMed PMID: 16264413 Keywords: Adult, Circadian Rhythm:physiology, Humans, Light, Lighting, Male, Melatonin:blood, Middle Aged, Photic Stimulation, Pupil:physiology, Retina:physiology, Signal Transduction:physiology,. Citation OBJECTIVES: Published data, both on nocturnal melatonin suppression in humans and on widely accepted retinal structure and function, sugge..... Read abstract Full text PDF