Brain aging and testosterone-induced neuroprotection: studies on cultured sheep cortical neurons. Lepore G, Zedda M, Mura E, Giua S, Dedola G, Farina V. Journal Article 2013; 34(5): 395-401 PubMed PMID: 23922037 Keywords: Aging:metabolism, Animals, Cerebral Cortex:cytology, DNA Topoisomerases, Type II:genetics, DNA-Binding Proteins:genetics, Neurons:cytology, Neuroprotective Agents:pharmacology, Sheep, Testosterone:pharmacology, Tyrosine:analogs & derivatives, Up-Regulatio. Citation OBJECTIVE: This research reports the expression of topoisomerase βII in fetal sheep neuronal cells. The β isoform of DNA topoisomerase I..... Read abstract Full text PDF