Articles by author - Michal Dubovický

Prenatal developmental toxicity study of the pyridoindole antioxidant SMe1EC2 in rats.

Ujhazy E, Dubovicky M, Ponechalova V, Navarova J, Brucknerova I, Snirc V, Mach M.

Journal Article 2008; 29(5): 639-643 PubMed PMID: 18987587  Keywords:  Abnormalities, Drug-Induced:pathology, Animals, Antioxidants:toxicity, Female, Fetal Development:drug effects, Fetal Diseases:chemically induced, Indoles:toxicity, Neuroprotective Agents:toxicity, Pregnancy, Pyridines:toxicity, Rats, Rats, Wistar, Reprodu.    Citation

OBJECTIVE: The 2-ethoxycarbonyl-8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyrido-[4,3b] indolinium chloride (SMe1EC2) is a prospective antioxid.....

Read abstract  Full text PDF

Reversible asphyxial status in a newborn due to neonatal form of carnitine palmitoyltransferase II deficiency.

Brucknerova I, Bzduch V, Behulova D, Ferianec V, Dubovicky M, Ujhazy E, Mach M.

Case Reports 2008; 29(5): 627-630 PubMed PMID: 18987586  Keywords:  Asphyxia Neonatorum:enzymology, Cardiopulmonary Resuscitation, Carnitine O-Palmitoyltransferase:deficiency, Heart Failure:etiology, Humans, Infant, Newborn, Male, Respiratory Insufficiency:etiology, Tandem Mass Spectrometry,.    Citation

OBJECTIVES: To present a term newborn with severe asphyxial status due to dysrrhythmia induced by the neonatal form of carnitine palmitoyl.....

Read abstract  Full text PDF

Nongenomic memory of foetal history in chronic diseases development.

Bezek S, Ujhazy E, Dubovicky M, Mach M.

Journal Article 2008; 29(5): 620-626 PubMed PMID: 18987584  Keywords:  Adult, Animals, Chronic Disease:epidemiology, Environment, Female, Fetal Development:genetics, Fetus:physiology, Humans, Pregnancy, Young Adult,.    Citation

: Foetal growth from conception to birth is a complex process predetermined by the genetic configuration of the foetus, the availability o.....

Read abstract  Full text PDF

Diurnal behavioral and endocrine effects of chronic shaker stress in mice.

Dubovicky M, Mach M, Key M, Morris M, Paton S, Lucot J.

Journal Article 2007; 28(6): 846-853 PubMed PMID: 18063939  Keywords:  Analysis of Variance, Animals, Chronic Disease, Circadian Rhythm:physiology, Corticosterone:blood, Disease Models, Animal, Exploratory Behavior:physiology, Male, Mice, Mice, Inbred C57BL, Motor Activity, Oxytocin:blood, Photoperiod, Stress, Physiological:.    Citation

: Experiments were performed in C57BL/6J male mice to determine 1) light/dark effects of acute and chronic shaker stress on open field beh.....

Read abstract  Full text PDF

Content of protein carbonyl groups in gerbil brain after reversible bilateral carotid occlusion: effect of 2,3-dihydromelatonin.

Ondrejicková O, Rapková M, Snirc V, Dubovický M, Jariabka P, Zacharová S, Stolc S.

Journal Article 2006; 27(Suppl 2): 156-159 PubMed PMID: 17159804  Keywords:  Animals, Arterial Occlusive Diseases:pathology, Brain Chemistry:drug effects, Carotid Arteries, Gerbillinae, Glutathione:analysis, Ischemic Attack, Transient:pathology, Male, Malondialdehyde:analysis, Melatonin:analogs & derivatives, Protein Carbonylation.    Citation

OBJECTIVES: To investigate whether a new derivative of melatonin, (2,3-dihydromelatonin (DHM), prevented the oxidative stress induced by i.....

Read abstract

Neurobehavioural changes in rats after neonatal anoxia: effect of antioxidant stobadine pretreatment.

Ujházy E, Schmidtová M, Dubovický M, Navarova J, Brucknerová I, Mach M.

Evaluation Studies 2006; 27(Suppl 2): 82-85 PubMed PMID: 17159786  Keywords:  Animals, Animals, Newborn, Antioxidants:therapeutic use, Behavior, Animal:drug effects, Carbolines:therapeutic use, Female, Growth and Development:drug effects, Hypoxia:pathology, Male, Motor Activity:drug effects, Pregnancy, Pregnancy, Animal, Premedicat.    Citation

OBJECTIVES: The aim of this study was to evaluate the effect of the synthetic pyridoindole antioxidant stobadine (STO, 50mg/kg/day) on beh.....

Read abstract