: MALDI-TOF mass spectrometry, 1H NMR spectrometry, the continuous variation method and molecular modeling by MM3 calculation confirmed our earlier studies showing that gonadotropin-releasing hormone (GnRH) forms complex with copper(II) ion with the binding ratio 1:1. The copper(II) complex formed at physiological pH has a square planar configuration and GnRH complexes with nickel(II) and cobalt(II) ions are less stable than that of copper(II).
ISSN: 0172-780X |
ISSN-L: 0172-780X |
eISSN 2354-4716
www.nel.edu Editor-in-Chief: Peter G. Fedor-Freybergh
www.nel.edu Editor-in-Chief: Peter G. Fedor-Freybergh