Barta F, Levova K, Hodek P, Schmeiser H, Arlt V, Stiborova M.
Journal Article 2015; 36(Suppl 1): 13-21 PubMed PMID: 26757129 Keywords: Animals, Aristolochic Acids:metabolism, Arsenic:pharmacology, Balkan Nephropathy, Cadmium:pharmacology, Carcinogens:metabolism, Chromatography, High Pressure Liquid, Ions, Lead:pharmacology, Metals, Heavy:pharmacology, Microsomes, Liver:metabolism, Ochrat. CitationOBJECTIVES: Balkan endemic nephropathy (BEN) is a chronic progressive fibrosis associated with upper urothelial carcinoma (UUC). Aetiology.....
Barta F, Levova K, Hodek P, Schmeiser H, Arlt V, Stiborova M. The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 13-21
Bostikova Z, Moserova M, Pavek P, Stiborova M, Hodek P.
Journal Article 2015; 36(Suppl 1): 46-52 PubMed PMID: 26757127 Keywords: Animals, Carcinogens:metabolism, Cytochrome P-450 Enzyme System:drug effects, Flavonols:pharmacology, Inhibitory Concentration 50, Intestine, Small:drug effects, Liver:drug effects, Male, RNA, Messenger:drug effects, Rats, Rats, Wistar, Real-Time Polymera. CitationOBJECTIVES: Dihydromyricetin (DHM) is a flavonoid, which has been shown to antagonize effects of ethanol intoxication. As a potential phar.....
Bostikova Z, Moserova M, Pavek P, Stiborova M, Hodek P. Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 46-52
Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M.
Journal Article 2015; 36(Suppl 1): 38-45 PubMed PMID: 26757124 Keywords: Animals, Antibodies:immunology, Antibody Formation, Blotting, Western, Cell Line, Tumor, Chickens, Cytochrome P-450 Enzyme System:immunology, Cytochrome P450 Family 2, Eggs, Electrophoresis, Gel, Two-Dimensional, Enzyme-Linked Immunosorbent Assay, Humans,. CitationOBJECTIVES: Cytochromes P450 (CYP) are monooxygenases, which metabolize mostly hydrophobic endogenous and exogenous compounds. CYPs withou.....
Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M. Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 38-45
Stiborova M, Manhartova Z, Hodek P, Adam V, Kizek R, Eckschlager T, Frei E.
Journal Article 2015; 36(Suppl 1): 22-28 PubMed PMID: 26757112 Keywords: Animals, Antineoplastic Agents:pharmacology, Cell Survival:drug effects, DNA Adducts:drug effects, Ellipticines:pharmacology, HL-60 Cells, Humans, In Vitro Techniques, Liver:drug effects, Micelles, Rats,. CitationOBJECTIVES: The improvements of cancer treatment are the major challenge in oncology research. Nanocarriers are one of the promising appro.....
Stiborova M, Manhartova Z, Hodek P, Adam V, Kizek R, Eckschlager T, Frei E. Cytotoxicity of and DNA adduct formation by ellipticine and its micellar form in human leukemia cells in vitro. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 22-28
Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M.
Journal Article 2014; 35(Suppl 2): 158-168 PubMed PMID: 25638381 Keywords: Animals, Benzo(a)pyrene:administration & dosage, Carcinogens:administration & dosage, DNA Adducts:administration & dosage, Flavonols:administration & dosage, Male, Rats, Rats, Wistar,. CitationOBJECTIVES: Flavanol dihydromyricetin (DHM) has been shown to counteract acute ethanol (EtOH) intoxication and reduce excessive E.....
Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M. Effect of dihydromyricetin on benzo[a]pyrene activation in rats. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 158-168
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H.
Journal Article 2014; 35(Suppl 2): 123-132 PubMed PMID: 25638376 Keywords: Animals, Aristolochic Acids:metabolism, Dicumarol:pharmacology, Enzyme Inhibitors:pharmacology, Humans, Quinone Reductases:metabolism, Rats,. CitationOBJECTIVES: Dicoumarol is known to act as an inhibitor of
NAD(P)H: quinone oxidoreductase (NQO1). T.....
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H. Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 123-132