Toxicological aspects of flavonoid interaction with biomacromolecules. Hodek P, Hanustiak P, Krízková J, Mikelova R, Krízková S, Stiborová M, Trnková L, Horna A, Beklová M, Kizek R. Journal Article 2006; 27(Suppl 2): 14-17 PubMed PMID: 17159770 Keywords: Adenine:metabolism, Animals, Colon:drug effects, Cytochrome P-450 CYP1A1:metabolism, DNA, Single-Stranded:metabolism, Electrochemistry, Enzyme Activation:drug effects, Flavonoids:metabolism, Guanidine:metabolism, Male, Microsomes, Liver:drug effects, Mode. Citation OBJECTIVES: Flavonoids are widely accepted as health promoting phytochemicals, however, some flavonoids show ability of direct interaction..... Read abstract