Plasma homocysteine in Alzheimer's disease with or without co-morbid depressive symptoms.

Comparative Study 2014; 35(1): 42-49 PubMed PMID: 24625917 Keywords: Age Factors, Aged, Aged, 80 and over, Alzheimer Disease:blood, Biomarkers:blood, Comorbidity, Depressive Disorder:blood, Female, Homocysteine:blood, Humans, Male, Middle Aged, Severity of Illness Index,.

OBJECTIVE: Elevated homocysteine is associated with a variety of diseases, including Alzheimer's disease (AD) and depressive disorder. Thi.....

In vitro effects of acetylcholinesterase inhibitors and reactivators on Complex I of electron transport chain.

Journal Article 2011; 32(3): 259-263 PubMed PMID: 21712782 Keywords: Animals, Brain Chemistry:drug effects, Cholinesterase Inhibitors:pharmacology, Cholinesterase Reactivators:pharmacology, Electron Transport:drug effects, Electron Transport Chain Complex Proteins:antagonists & inhibitors, Electron Transport Complex I:meta.

OBJECTIVES: Inhibition of the enzyme acetylcholinesterase (AChE) is the main mechanism both of therapeutic action of drugs for the treatme.....

Journal Article 2010; 31(5): 645-656 PubMed PMID: 21200377 Keywords: Affect:drug effects, Amitriptyline:pharmacology, Animals, Antidepressive Agents:pharmacology, Antimanic Agents:pharmacology, Benzodiazepines:pharmacology, Cerebral Cortex:cytology, Citalopram:pharmacology, Clorgyline:pharmacology, Cocaine:pharmacology, Cy.

OBJECTIVE: Monoamine oxidase (MAO), the enzyme responsible for metabolism of monoamine neurotransmitters, has an important role in the bra.....

Comparative Study 2010; 31(3): 336-342 PubMed PMID: 20588251 Keywords: Animals, Antidepressive Agents:pharmacology, Antipsychotic Agents:pharmacology, Benzodiazepines:pharmacology, Cerebral Cortex:drug effects, Citrate (si)-Synthase:metabolism, Electron Transport:drug effects, Electron Transport Complex I:metabolism, Electro.

OBJECTIVE: Mitochondrial dysfunctions, impaired bioenergetics and dysfunction of neurotrophins are included in many neurodegenerative and .....