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Journal Article 2007; 28(Suppl 2): 47-48 PubMed PMID: 17558382 Citation  Keywords:  Adolescent, Adult, Aged, Anti-Infective Agents:therapeutic use, Bacteremia:complications, Central Nervous System Diseases:etiology, Child, Child, Preschool, Cohort Studies, Endocarditis, Bacterial:complications, Enterococcus, Gram-Positive Bacterial Infec.   

: Within a cohort of 606 cases of infective endocarditis, 263 were complicated and 99 embolizing, of them 32 to the central nervous system (CNS). Significant predictors of CNS embolisation were inappropriate therapy (p<0.01) and enterococcal etiology (p<0.01). Mortality in patients with CNS emboli was 65% what was significantly higher than in cases without embolisation - 15% (p<0.01)....

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Journal Article 2007; 28(Suppl 2): 38-39 PubMed PMID: 17558378 Citation  Keywords:  Anti-Infective Agents:therapeutic use, Brain Diseases:drug therapy, Candidiasis:drug therapy, Cross Infection:drug therapy, Drug Resistance, Microbial, Fluconazole:therapeutic use, Humans, Meningitis:drug therapy, Pseudomonas Infections:drug therapy, Stap.   

: Within last 15 years, analyzing patterns of etiology and resistance in organisms causing neuroinfections, emergence of resistance has been observed in Slovakia in S. haemolyticus to teicoplanin (11%), Ps. aeruginosa and A. baumannii to meropenem (20%) and Candida spp. (non-albicans Candida spp.) to fluconazol (20%). There are no new antibiotics against carbapenem resistant Ps. aeruginosa and Acinetobacter baumannii....

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Journal Article 2007; 28(Suppl 2): 22-24 PubMed PMID: 17558371 Citation  Keywords:  Aneurysm, Infected:etiology, Anti-Infective Agents:therapeutic use, Bacterial Infections:complications, Brain:microbiology, Central Nervous System Diseases:etiology, Cerebrovascular Disorders:etiology, Endocarditis:complications, Humans, Meningitis:etiolo.   

: Neurologic complications of infective endocarditis, risk factors for mortality and neurologic sequellae are briefly reviewed....

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Journal Article 2007; 28(Suppl 2): 7-10 PubMed PMID: 17558365 Citation  Keywords:  Anti-Infective Agents:therapeutic use, Cerebrovascular Disorders:etiology, Cross Infection:etiology, Humans, Meningitis:etiology, Postoperative Complications:etiology, Risk Factors,.   

: Nosocomial cerebrovacsular infections are substantial cause of mortality and morbidity in patients after neurosurgery. Risk factors, etiology, treatment strategies and outcome of nosocomial meningitis and brain abscess are briefly reviewed....

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Journal Article 2006; 27(6): 741-744 PubMed PMID: 17187016 Citation  Keywords:  Adrenal Cortex Hormones:therapeutic use, Aged, Aged, 80 and over, Anti-Infective Agents:therapeutic use, Chi-Square Distribution, Chronic Disease, Complement C3:analysis, Conjunctivitis:complications, Dry Eye Syndromes:complications, Female, Humans, Immun.   

PURPOSE: The aim of this study was a clinical analysis of patients with symptoms typical of pemphigoid.

MATERIAL AND METHODS: 21 patients were enrolled on the study within the period 1988-2004. The frequency and type of ophthalmological and extraocular symptoms and accompanying diseases were assessed. The analysis also contains immunological findings as well as administered treatment.

RESULTS: Ophthalmological changes were detected in 100% of examined patients with pemphigoid. The most frequent were dry eye syndrome and conjunctivitis. Immunohistochemical tests revealed the presence of antibodies in 68.2% of the examined cases. All patients required specific treatment--local, general and surgical. Despite the administered therapy the development of cicatricial changes was observed.

CONCLUSIONS: Chronic conjunctivitis and keratitis require diagnostics into pemphigoid. Intensive therapy is necessary in patients with ocular cicatricial pemphigoid (OCP) because of high risk of blindness. Delayed diagnostics disable immunohistochemical confirmation of disease....

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