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Case Reports 2015; 36(1): 24-27 PubMed PMID: 25789591 Citation  Keywords:  Chelation Therapy:methods, Humans, Iron:metabolism, Iron Chelating Agents:therapeutic use, Male, Middle Aged, Parkinson Disease:drug therapy, Treatment Outcome,.   

: In this case presentation, a man with a diagnosis of Parkinson's disease was treated with Chelation Therapy against iron without iron serum level correlation. The patient, who suffered from motor and non-motor symptoms of the disease, showed an improved condition after the Therapy. This clinical test was evaluated with UPDRS III score. The rationale and the limits of the Therapy are discussed. This case suggests that iron-dependent oxidative stress could represent a promising therapy for this dramatic disease; the necessity to deeply study the iron metabolism in neuro-degeneration appears really significant....

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Case Reports 2013; 34(6): 504-507 PubMed PMID: 24378455 Citation  Keywords:  Aged, Aluminum:blood, Alzheimer Disease:drug therapy, Antioxidants:therapeutic use, Ascorbic Acid:therapeutic use, Chelation Therapy:methods, Deferoxamine:therapeutic use, Epilepsy:drug therapy, Fatal Outcome, Female, Humans, Iron:blood, Siderophores:ther.   

: In this case presentation, a woman with high serum levels of aluminum was treated with chelation therapy with deferoxamine and ascorbic acid. This patient was initially bedridden and the clinical situation was complicated by epileptic seizures. After the chelation therapy, the clinical condition was ameliorated and the therapy continued without the correlation to aluminum serum levels. The role of metals in neurodegenerative disorders and the correlation between iron metabolism and amyloid beta peptide are described. This case suggests chelation therapy could represent a promising therapeutic option for this dramatic disease....

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