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Meningitis in diabetic patients.

Muli J, Seckova S, Sladeckova V, Steno J, Adamcova J, Rabarova L, Takacova M, Polonova J, Dudasova T, Pauerova K, Namulanda V, Okoth V, Juma O, Diana E, Johnson M, Deadline J, Bartkovjak M, Kolenova A, Taziarova M, Benca J, Njambi Z.
Journal Article 2007; 28(Suppl 3): 28-29 PubMed PMID: 18030274 Citation  Keywords:  Anti-Bacterial Agents:therapeutic use, Cefotaxime:therapeutic use, Cohort Studies, Community-Acquired Infections:microbiology, Diabetes Complications:immunology, Diabetes Mellitus:immunology, Humans, Meningitis, Bacterial:etiology, Outcome Assessment (Hea.   

: Community acquired bacterial (CBM) meningitis in diabetic patients was analyzed for risk factors and outcome in a cohort of 201 cases of meningitis within last 17 years: 15 patients with diabetes mellitus and meningitis were identified and compared for etiology and mortality as well as for neurologic sequellae with all CBM cases....

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Gram-negative bacillary community acquired meningitis is not a rare entity in last two decades.

Taziarova M, Holeckova K, Lesnakova A, Sladeckova V, Bartkovjak M, Seckova S, Bukovinova P, Hvizdak F, Svabova V, Findova L, Kisac P, Beno P, Bauer F, Bauer M, Karvaj M, Rudinsky B, Sabo I, Bielova M, Luzica R, Wiczmandyova O, Huttova M, Ondrusova A.
Comparative Study 2007; 28(Suppl 3): 18-19 PubMed PMID: 18030268 Citation  Keywords:  Chi-Square Distribution, Community-Acquired Infections:microbiology, Cross Infection:microbiology, Gram-Negative Bacteria:classification, Gram-Negative Bacterial Infections:complications, Humans, Infant, Newborn, Meningitis, Bacterial:complications, Outco.   

: The aim of this short note is to assess gram-negative bacillary community acquired meningitis (CBM) and nosocomial meningitis (NM) within 17 years nationwide survey. All cases of gram-negative bacillary CBM within 1990-2007 were assessed in national database of 372 patients with bacterial meningitis: 69 of gram-negative cases were nosocomial and 24 of gram-negative meningitis cases were CBM. Those 24 cases were compared with all CBM (201 cases) for risk factors and outcome. Among nosocomial gram-negative pathogens, A. baumannii in 23 cases, Ps. aeruginosa in 15 cases and Enterobacteriaceae in 31 cases were isolated. Among CBM, in 13 cases Enterobacteriaceae (Escherichia coli 6, Klebsiella pneumoniae 3, Proteus mirabilis 2, Enterobacter cloacae 2), in 5 cases Ps. aeruginosa and in 6 cases Acinetobacter baumannii were isolated from cerebrospinal fluid (CSF). The only significant risk factor for CBM due to gram-negative bacilli was neonatal age (12.5% vs. 3.5%, p=0.04) as underlying disease. However, mortality among gram-negative bacillary meningitis was significantly higher (12.4% vs. 37.5%, p=0.001) in comparison to other meningitis....

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