Search NEL Online

Sort by relevance:
Search in:

Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.

Witek B, Ochwanowska E, Rafay J, Kolataj A, Chrenek P, Suvegova K, Jurcik R, Sirotkin A, Darlak K.
Journal Article 2005; 26(4): 397-400 PubMed PMID: 16136002 Citation  Keywords:  Acid Phosphatase:blood, Animals, Antigens, CD13:blood, Cathepsin D:blood, Cathepsin L, Cathepsins:blood, Cysteine Endopeptidases:blood, Esterases:blood, Female, Ghrelin, Homeostasis:drug effects, Hydrolases:blood, Lipase:blood, Lysosomes:enzymology, Pepti.   

OBJECTIVES: Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight.

METHODS: In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined.

RESULTS: As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly.

CONCLUSION: Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system....

Read abstract  Full text PDF