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Case Reports 2015; 36(1): 96-99 PubMed PMID: 25789592 Citation  Keywords:  Aged, Exercise Therapy:methods, Fatigue Syndrome, Chronic:physiopathology, Humans, Male, Physical Exertion:physiology,.   

: A Graded Exercise Therapy (GET) - Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) Running Anomaly. Imagine you have been disabled with ME/CFS's cluster of symptoms for 19 years. Yet, this morning you just ran an easy 10K with no flare up of your exercise intolerance symptoms during the run or post-exertional malaise after the run. Then later in the day you go browsing for books and after 30 minutes or so your exercise intolerance and post-exertional malaise symptoms flare up. You experience a wave of exhaustion, achy muscles and additional cognitive fog, all of which carry into the next day. To me, this is a confusing anomaly that needs an explanation....

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Journal Article 2007; 28(5): 675-680 PubMed PMID: 17984945 Citation  Keywords:  Adolescent, Adult, Copper:blood, Exercise:physiology, Humans, Male, Oxygen Consumption:physiology, Physical Exertion:physiology, Reference Values, Statistics, Nonparametric, Zinc:blood,.   

: This study was carried out in order to determine the effect of acute maximal aerobic exercise on the copper and zinc levels in blood. The study was participated by 16 healthy male university students with an average age of 19.44+/-1.63. There were 5 cc blood samples taken from the participants before and after they had been subjected to aerobic loading process (20 m shuttle run). The copper and zinc levels in the blood samples were determined by the use of Anodic Stripping Voltammetry (ASV) technique. The data obtained were evaluated by simple t test and SPSS software. The results revealed the fact that the blood Zn levels of the participants increased and Cu levels decreased with statistical significant extent (p<0.01) after maximal aerobic loading. There found no correlation between the maximal aerobic power levels (Max VO2) of the participants and their resting copper and zinc blood levels. However blood zinc and Max VO2 levels of the participants were positively correlated after maximal aerobic loading. The participants were fed on a zinc and copper free diet six week prior to the program. They were also asked not to use copper and zinc containing vitamins during this period....

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Clinical Trial 2007; 28(5): 681-685 PubMed PMID: 17984944 Citation  Keywords:  Administration, Oral, Adolescent, Adult, Dietary Supplements, Exercise:physiology, Exercise Test, Fatigue:blood, Humans, Male, Physical Exertion:physiology, Testosterone:blood, Thyroid Hormones:blood, Thyroxine:blood, Trace Elements:administration & dosag.   

OBJECTIVE: The aim of this study was to determine how exercise affects thyroid hormones and testosterone levels in sedentary men receiving oral zinc for 4 weeks.

METHODS: The study included 10 volunteers (mean age, 19.47+/-1.7 years) who did not exercise. All subjects received supplements of oral zinc sulfate (3 mg/kg/day) for 4 weeks and their normal diets. The thyroid hormone and testosterone levels of all subjects were determined at rest and after bicycle exercise before and after zinc supplementation.

RESULTS: TT3, TT4, FT3, and total and free testosterone levels decreased after exercise compared to resting levels before supplementation (p<0.01). Both the resting and fatigue hormone values were higher after 4 weeks of supplementation than the resting and fatigue values before supplementation (p<0.05).

CONCLUSION: The results indicate that exercise decreases thyroid hormones and testosterone in sedentary men; however, zinc supplementation prevents this decrease. Administration of a physiologic dose of zinc can be beneficial to performance....

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Clinical Trial 2007; 28(5): 708-712 PubMed PMID: 17984925 Citation  Keywords:  Adolescent, Adult, Analysis of Variance, Dietary Supplements, Exercise:physiology, Humans, Magnesium:administration & dosage, Martial Arts:physiology, Physical Exertion:physiology, Reference Values, Rest:physiology, Statistics, Nonparametric, Thyroid Horm.   

: The effect of magnesium on thyroid hormones of sedentars and sportsperson in Tae-Kwon-Do, has been investigated in a 4-weeks training program. Group 1 consisted of sedentars receiving 10 mg/kg/day Mg for 4 weeks. Group 2 consisted of subjects receiving magnesium (Mg) supplement and practicing Tae-Kwon-Do for 90-120 min/day, for five days a week. Group 3 consisted of subjects practicing Tae-Kwon-Do but receiving Mg supplements. TSH levels increased with training and Mg supplementation (p<0.05). Mg increased FT3 values. (p<0.05). TT3 values of groups reduced in all groups (p<005). After supplementation, group 1 had higher TT4 values than groups 1 and 3 and the group 2 had higher TT4 values than the third group (p<005). Results of this research show that training until exhaustion causes reduction in thyroid hormone activity in sedentars and sportsperson. It has been established that Mg supplementation however, prevents reduction in thyroid hormone activity in sedentars and sportsperson....

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Clinical Trial 2007; 28(2): 187-190 PubMed PMID: 17435664 Citation  Keywords:  Air Pollutants:analysis, Basketball, Exercise, Humans, Lead:blood, Male, Physical Exertion, Respiration,.   

: This study is related to the investigation of the Pb levels in blood of the 12 healthy University male basketball players before and after a strenuous training session by the use of square wave anodic stripping voltammetry. Although the results do not show acute lead intoxication it is obvious that blood lead levels show significant increase after training sessions. The average increase in blood lead levels is 297%. This increase is largely due to increased respiration rate during the training period....

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Clinical Trial 2005; 26(6): 830-834 PubMed PMID: 16380698 Citation  Keywords:  Adult, Analysis of Variance, Energy Metabolism:physiology, Exercise:physiology, Heart Rate:physiology, Humans, Male, Physical Exertion, Reference Values, Statistics, Nonparametric, Thyrotropin:blood, Thyroxine:blood, Triiodothyronine:blood,.   

BACKGROUND: Physical activity influences energy metabolism in human subjects by increasing activity-induced energy expenditure and resting metabolic rate for several hours after exercise. Effects of exercise on circulating thyroid hormone values remain controversial. We have investigated the effect of acute aerobic exercise on thyroid hormone values.

MATERIALS/METHODS: The effect of different intensity levels of acute aerobic exercise on thyroid hormones was investigated in 60 male well-trained athletes by performing bicycle ergometer at 45% (low intensity), 70% (moderate intensity), and 90% (high intensity). These intensities were selected according to their maximum heart rate (MHR). At each intensity level, heart rate, blood lactic acid, serum total thyroxine (T4), free thyroxine (fT4), total triiodothyronine (T3), free triiodothyronine (fT3) and thyroid stimulating hormone (TSH) values were measured.

RESULTS: The results of this study show that exercise performed at the anaerobic threshold (70% of maximum heart rate, lactate level 4.59 +/- 1.75 mmol/l) caused the most prominent changes in the amount of any hormone values. While the rate of T4, fT4, and TSH continued to rise at 90% of maximum heart rate, the rate of T3 and fT3 started to fall.

CONCLUSIONS: Maximal aerobic exercise greatly affects the level of circulating thyroid hormones....

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Journal Article 2005; 26(4): 297-300 PubMed PMID: 16136023 Citation  Keywords:  Adult, Estradiol:blood, Female, Follicle Stimulating Hormone:blood, Glycolysis:physiology, Humans, Leptin:blood, Luteinizing Hormone:blood, Menstrual Cycle:physiology, Physical Exertion:physiology, Progesterone:blood,.   

OBJECTIVES: It was aimed to determine whether there was a difference in the leptin levels and short term exercise performance during the menstrual cycle of the young females who had normal menstrual cycle and no pregnancy story.

SETTING AND DESIGN: Fifteen sedentary females aged 19-23 yrs were included. All had regular menstrual cycle of 28-30 days and no pregnancy story. Blood samples were taken for the analysis of serum estradiol, progesterone and leptin levels and Wingate test was applied on a Monark 818E ergometer with 75 g/kg load on the 7th, 14th and 21st cycle days, randomly.

RESULTS: The differences in serum leptin levels and peak power, mean power and fatigue index during these days and the correlations between serum leptin and FSH, LH, estradiol and progesterone levels were not significant.

CONCLUSIONS: We concluded that performance in a short intense exercise which require high motivation is not affected by menstrual cycle and in young females with normal menstrual cycle, serum leptin concentration does not change during the cycle. Further studies constituting more standard groups, controlling food intake, timing the blood sampling, studying more days of menstrual cycle will help to obtain more accurate results....

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