OBJECTIVE: Reported brain abnormalities in anatomy and function in psychiatric and neurological patients led to a project based on qualitative electroencephalography examination and analysis in an attempt to find specific brain derived pattern--or sequence of brain locations involved in processing various stimuli--both visual and auditory.
Susta M, Papezova H, Petranek S, Sonka K. Brain activation sequences. Neuro Endocrinol Lett. 2015 Jan; 36(8): 758-766
OBJECTIVE: Uterine sarcomas are rare mesodermal malignant tumors with an incidence between 0.5 and 3.3 cases per 100,000 females per year. Most sarcomas are aggressive tumors leading to poor overall survival rates and only limited therapeutic options. The aim of this study was to evaluate the risk factors for uterine sarcomas and carcinosarcomas, and to identify the factors influencing the survival rate.
Visnovsky J, Kudela E, Slavik P, Krkoska M, Buocik P, Szepe P, Danko J. Survival and risk factors associated with uterine sarcomas and carcinosarcomas in stage I and II. Neuro Endocrinol Lett. 2015 Jan; 36(8): 750-757
OBJECTIVE: Hyperprolactinemia is associated with bone fragility. Traditionally attributed to prolactin-induced hypogonadism, recent studies have identified increased fracture rates independent of gonadal function.
D'Sylva C, Khan T, Van Uum S, Fraser L. Osteoporotic fractures in patients with untreated hyperprolactinemia vs. those taking dopamine agonists: A systematic review and meta-analysis. Neuro Endocrinol Lett. 2015 Jan; 36(8): 745-749
OBJECTIVES: Our goal is to demonstrate the variability of imaging findings, primarily in the MRI, in 46 patients who survived acute methanol poisoning. This cohort of patients is the largest such sample group examined by MRI.
Vaneckova M, Zakharov S, Klempir J, Ruzicka E, Bezdicek O, Brozova H, Diblik P, Miovsky M, Hubacek J, Urban P, Ridzon P, Pelclova D, Burgetova A, Masek M, Kotikova K, Peterova K, Liskova I, Hamplova L, Seidl Z. Imaging findings after methanol intoxication (cohort of 46 patients). Neuro Endocrinol Lett. 2015 Jan; 36(8): 737-744
: Turner syndrome (TS) is a congenital disease caused by absence or structural abnormalities of sex chromosomes resulting in gonadal dysgenesis. Spontaneous pregnancies occur in 2-8% of patients, especially with mosaic kariotypes, however they are associated with increased risk of poor outcome both for mother and fetus. We report a 4-day-old male infant delivered by women with mosaic TS who was admitted to the pediatric intensive care unit and presented with severe panhypopituitarism as the early manifestation of pituitary stalk interruption syndrome (PSIS). To the best of our knowledge this is the first report of severe panhypopituitarism in a newborn borne by women with TS....
Olszewska M, Kiełbasa G, Wójcik M, Zygmunt-Górska A, Starzyk J. A case report of severe panhypopituitarism in a newborn delivered by a women with Turner syndrome. Neuro Endocrinol Lett. 2015 Jan; 36(8): 734-736
: At birth, a male child presented a 6 cm tumour in the right leg. The tumour was partially removed after just 12 days. Histology showed a congenital fibrosarcoma associated with reactive lymphadenitis. A first cycle of adjuvant chemotherapy did not prevent the rapid progression of the disease. Subsequent evaluation for surgical removal raised serious concerns due to the need for a major operation involving total amputation of the right leg and hemipelvectomy. Since surgery could not exclude the possibility of disease recurrence and since the traditional cycles of chemotherapy did not offer any possibility of a cure, the parents opted for the Di Bella Method. The combined use of Somatostatin, Melatonin, Retinoids solubilized in Vit. E, Vit. C, Vit. D3, Calcium, and Chondroitin sulfate associated with low doses of Cyclophosphamide resulted in a complete objective response, still present 14 years later, with no toxicity and without the need for hospitalization, allowing a normal quality of life and perfectly normal adolescent psycho-physical development....
Di Bella G, Toscano R, Ricchi A, Colori B. Congenital fibrosarcoma in complete remission with Somatostatin, Bromocriptine, Retinoids, Vitamin D3, Vitamin E, Vitamin C, Melatonin, Calcium, Chondroitin sulfate associated with low doses of Cyclophosphamide in a 14-year Follow up. Neuro Endocrinol Lett. 2015 Jan; 36(8): 725-733
OBJECTIVES: Authors discuss the case of a suicide of a 29-year-old man caused by carbon monoxide (CO) intoxication. What the authors found interesting was the unusual way of committing suicide that required good technical skills and expert knowledge.
Zelený M, Pivnička J, Šindler M, Kukleta P. Unusual way of suicide by carbon monoxide. Case Report. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 147-149
OBJECTIVES: Balkan endemic nephropathy (BEN) is a chronic progressive fibrosis associated with upper urothelial carcinoma (UUC). Aetiology of BEN is still not fully explained. Although carcinogenic aristolochic acid I (AAI) was proven as the major cause of BEN/UUC, this nephropathy is considered to be multifactorial. Hence, we investigated whether other factors considered as potential causes of BEN [a mycotoxin ochratoxin A (OTA), Cd, Pb, Se and As ions and organic compounds (i.e. phthalates) released from lignite deposits in BEN areas] can influence detoxication of AAI, whose concentrations are crucial for BEN development.
Barta F, Levova K, Hodek P, Schmeiser H, Arlt V, Stiborova M. The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 13-21