Importance of thiopurine S-Methyltransferase gene polymorphisms for prediction of azathioprine toxicity. Kolorz M, Bartosova L, Hosek J, Dvorackova D, Chylkova A, Zboril V, Batovsky M, Bartos M. Journal Article 2009; 30(Suppl 1): 137-142 PubMed PMID: 20027160 Keywords: Adult, Alleles, Azathioprine:adverse effects, Female, Genetic Predisposition to Disease, Genotype, Humans, Leukopenia:chemically induced, Male, Methyltransferases:genetics, Polymerase Chain Reaction, Polymorphism, Genetic, Polymorphism, Single Nucleotide,. Citation OBJECTIVES: Our study aims to find the relationship between metabolic enzyme thiopurine S-methyltransferase (TPMT) gene polymorphisms and ..... Read abstract Full text PDF