Heger Z, Zitka O, Krizkova S, Beklova M, Kizek R, Adam V.
Journal Article 2013; 34(Suppl 2): 123-129 PubMed PMID: 24362104 Keywords: Animals, Cell Proliferation:drug effects, Estradiol:metabolism, Gene Expression Regulation:drug effects, Humans, Male, Protein Binding:drug effects, Receptors, Estrogen:metabolism, Response Elements:drug effects,. Citation: Group of estrogen pollutants, where the highest estrogen activity is reported at estradiol, is characterized by the fact that even at ve.....
Heger Z, Zitka O, Krizkova S, Beklova M, Kizek R, Adam V. Molecular biology of beta-estradiol-estrogen receptor complex binding to estrogen response element and the effect on cell proliferation. Neuro Endocrinol Lett. 2013 Jan; 34(Suppl 2): 123-129
Hodek P, Krizkova J, Frei E, Singh R, Arlt V, Stiborova M.
Journal Article 2011; 32(Suppl 1): 25-34 PubMed PMID: 22167217 Keywords: Animals, Carcinogens, Environmental:isolation & purification, Cytochrome P-450 CYP1A1:antagonists & inhibitors, DNA Damage:drug effects, Drug Evaluation, Preclinical, Enzyme Induction:drug effects, Enzyme Inhibitors:pharmacology, Food:toxicity, Food Conta. CitationOBJECTIVES: Benzo[a]pyrene (BaP) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) are carcinogens, which frequently occur in the.....
Hodek P, Krizkova J, Frei E, Singh R, Arlt V, Stiborova M. Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens. Neuro Endocrinol Lett. 2011 Jan; 32(Suppl 1): 25-34
Hodek P, Tepla M, Krizkova J, Sulc M, Stiborova M.
Journal Article 2009; 30(Suppl 1): 67-71 PubMed PMID: 20027147 Keywords: Animals, Antioxidants:pharmacology, Benzoflavones:chemistry, Carbon Monoxide:metabolism, Cytochrome P-450 Enzyme System:metabolism, Cytochromes b5:metabolism, Cytochromes c:metabolism, Ferricyanides:metabolism, Flavonoids:chemistry, Fluorometry, Male, Mic. CitationOBJECTIVES: The aim of this study was to assess the effect of various flavonoids on the NADPH:cytochrome P450 oxidoreductase (CYPOR) activ.....
Hodek P, Tepla M, Krizkova J, Sulc M, Stiborova M. Modulation of cytochrome P450 enzyme system by selected flavonoids. Neuro Endocrinol Lett. 2009 Jan; 30(Suppl 1): 67-71
Krizkova J, Burdova K, Hudecek J, Stiborova M, Hodek P.
Journal Article 2008; 29(5): 717-721 PubMed PMID: 18987596 Keywords: Allyl Compounds:pharmacology, Animals, Anticarcinogenic Agents:pharmacology, Blotting, Western, Curcumin:pharmacology, Cytochrome P-450 CYP1A1:biosynthesis, Cytochrome P-450 CYP2B1:biosynthesis, Cytochrome P-450 Enzyme System:biosynthesis, Flavonoids:phar. CitationOBJECTIVES: Since flavonoids and other natural compounds exert beneficial effects on human health, their consumption rapidly increases. Ho.....
Krizkova J, Burdova K, Hudecek J, Stiborova M, Hodek P. Induction of cytochromes P450 in small intestine by chemopreventive compounds. Neuro Endocrinol Lett. 2008 Oct; 29(5): 717-721
Hodek P, Hanustiak P, Krízková J, Mikelova R, Krízková S, Stiborová M, Trnková L, Horna A, Beklová M, Kizek R.
Journal Article 2006; 27(Suppl 2): 14-17 PubMed PMID: 17159770 Keywords: Adenine:metabolism, Animals, Colon:drug effects, Cytochrome P-450 CYP1A1:metabolism, DNA, Single-Stranded:metabolism, Electrochemistry, Enzyme Activation:drug effects, Flavonoids:metabolism, Guanidine:metabolism, Male, Microsomes, Liver:drug effects, Mode. CitationOBJECTIVES: Flavonoids are widely accepted as health promoting phytochemicals, however, some flavonoids show ability of direct interaction.....
Hodek P, Hanustiak P, Krízková J, Mikelova R, Krízková S, Stiborová M, Trnková L, Horna A, Beklová M, Kizek R. Toxicological aspects of flavonoid interaction with biomacromolecules. Neuro Endocrinol Lett. 2006 Dec; 27(Suppl 2): 14-17