Articles by author - Jaroslav Kvetina

Caco-2 cell monolayer integrity and effect of probiotic Escherichia coli Nissle 1917 components.

Stetinova V, Smetanova L, Kvetina J, Svoboda Z, Zidek Z, Tlaskalova-Hogenova H.

Journal Article 2010; 31(Suppl 2): 51-56 PubMed PMID: 21187838  Keywords:  Adenocarcinoma:metabolism, Caco-2 Cells, Carbon Radioisotopes, Cell Membrane Permeability:drug effects, Cell Survival:drug effects, Colonic Neoplasms:metabolism, Dose-Response Relationship, Drug, Escherichia coli, Humans, Lipopolysaccharides:pharmacology,.    Citation

OBJECTIVES: Different probiotic strains used in clinical trials have shown prophylactic properties in different inflammatory diseases of t.....

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Pharmacokinetics and organ distribution of fluorescein in experimental pigs: an input study for confocal laser endomicroscopy of the gastrointestinal tract.

Kunes M, Kvetina J, Malakova J, Bures J, Kopacova M, Rejchrt S.

Journal Article 2010; 31(Suppl 2): 57-61 PubMed PMID: 21187822  Keywords:  Adipose Tissue:cytology, Animals, Blood-Brain Barrier, Brain:cytology, Female, Fluorescein:administration & dosage, Fluorescent Dyes:administration & dosage, Gastrointestinal Tract:cytology, Injections, Intravenous, Kidney:cytology, Lung:cytology, Microsc.    Citation

OBJECTIVE: Confocal laser scanning endomicroscopy (CLSE) is a diagnostic technology that produces virtual histology of the mucosal layer u.....

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Caco-2 cells and Biopharmaceutics Classification System (BCS) for prediction of transepithelial transport of xenobiotics (model drug: caffeine).

Smetanova L, Stetinova V, Kholova D, Kvetina J, Smetana J, Svoboda Z.

Journal Article 2009; 30(Suppl 1): 101-105 PubMed PMID: 20027153  Keywords:  Biological Transport:drug effects, Caco-2 Cells, Caffeine:pharmacokinetics, Cell Culture Techniques, Cell Survival:drug effects, Diffusion, Humans, Hydrogen-Ion Concentration, Intestinal Absorption, Intestinal Mucosa:metabolism, Kinetics, Linear Models, M.    Citation

OBJECTIVES: The Caco-2 cell monolayer model is widely used as a standard screening tool for studying the mechanisms of cellular drug trans.....

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Type and distribution of indomethacin-induced lesions in the gastrointestinal tract of rat.

Kunes M, Kvetina J, Bures J.

Journal Article 2009; 30(Suppl 1): 96-100 PubMed PMID: 20027152  Keywords:  Administration, Oral, Animals, Anti-Inflammatory Agents, Non-Steroidal:administration & dosage, Gastrointestinal Diseases:chemically induced, Indomethacin:administration & dosage, Intestines:drug effects, Male, Prospective Studies, Rats, Rats, Wistar, Sto.    Citation

OBJECTIVES: The therapy with non-steroidal anti-inflammatory drugs (e.g. indomethacin) is often accompanied with adverse effects in gastro.....

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The use of wireless capsule enteroscopy in a preclinical study: a novel diagnostic tool for indomethacin-induced gastrointestinal injury in experimental pigs.

Kvetina J, Kunes M, Bures J, Kopacova M, Tachecí I, Spelda S, Herout V, Rejchrt S.

Journal Article 2008; 29(5): 763-769 PubMed PMID: 18987574  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Capsule Endoscopy:methods, Female, Gastric Mucosa:pathology, Gastroscopy, Indomethacin:toxicity, Intestinal Mucosa:pathology, Microscopy, Confocal, Peptic Ulcer:chemically induced, Swine,.    Citation

OBJECTIVES: The aim was the utilization of capsule microscopy and other diagnostic techniques for prospective pre-clinical research of abs.....

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Effect of galantamine on acetylcholinesterase and butyrylcholinesterase activities in the presence of L-carnitine in rat selected brain and peripheral tissues.

Svoboda Z, Kvetina J, Kunesová G, Herink J, Bajgar J, Bartosová L, Zivný P, Palicka V.

Journal Article 2006; 27(Suppl 2): 183-186 PubMed PMID: 17159811  Keywords:  Acetylcholinesterase:blood, Animals, Brain:drug effects, Butyrylcholinesterase:blood, Carnitine:pharmacology, Cholinesterase Inhibitors:pharmacology, Galantamine:pharmacology, Liver:drug effects, Male, Pituitary Gland:drug effects, Rats, Rats, Wistar,.    Citation

OBJECTIVES: The alkaloid galantamine (GAL), which exhibits a combined anticholinesterase and direct parasympathomimetic mechanism of actio.....

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