The use of melatonin in Alzheimer's disease. Cardinali D, Brusco L, Liberczuk C, Furio A. Journal Article 2002; 23(Suppl 1): 20-23 PubMed PMID: 12019347 Keywords: Aged, Alzheimer Disease:complications, Antioxidants:therapeutic use, Circadian Rhythm:drug effects, Clinical Trials as Topic, Humans, Melatonin:therapeutic use, Sleep Wake Disorders:drug therapy,. Citation : About 45% of Alzheimer's disease (AD) patients have disruptions in their sleep and sundowning agitation. Since melatonin secretion is gr..... Read abstract