Articles by author - Vaclav Martínek

A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Semanska M, Dracinsky M, Martinek V, Hudecek J, Hodek P, Frei E, Stiborova M.

Journal Article 2008; 29(5): 712-716 PubMed PMID: 18987613  Keywords:  Carcinogens:chemistry, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Electrons, Horseradish Peroxidase:chemistry, Hydrogen Peroxide:chemistry, Magnetic Resonance Spectroscopy, Mass Spectrometry, Naphthols:chemistry, Oxidation-Reduction.    Citation

OBJECTIVES: The aim of the study was to examine oxidation of carcinogenic Sudan I by peroxidase and characterize the structure of its two .....

Read abstract  Full text PDF

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser H, Frei E.

Journal Article 2006; 27(Suppl 2): 35-39 PubMed PMID: 17159775  Keywords:  Animals, Coloring Agents:pharmacokinetics, Cytochrome P-450 CYP1A1:metabolism, Cytochromes b5:physiology, DNA:metabolism, DNA Adducts:metabolism, Humans, Male, Metabolic Detoxication, Phase I, Models, Biological, Naphthols:metabolism, Rabbits, Rats, Rats,.    Citation

OBJECTIVES: Modulation of the cytochrome P450 (CYP) 1A1-mediated oxidative activation and detoxication of carcinogenic Sudan I by the heme.....

Read abstract

Expression of nitric oxide synthases in parathyroid gland adenoma and parathyroid gland hyperplasia.

Kucera T, Veselý D, Pácová H, Martínek J, Astl J.

Journal Article 2005; 26(4): 373-376 PubMed PMID: 16136006  Keywords:  Adenoma:blood supply, Apoptosis, Humans, Hyperplasia, Immunoenzyme Techniques, Neovascularization, Pathologic:metabolism, Nitric Oxide Synthase Type II:metabolism, Nitric Oxide Synthase Type III:metabolism, Parathyroid Glands:blood supply, Parathyroid Neo.    Citation

OBJECTIVE: The aim of the presented study was to perform the immunohistochemical detection of endothelial (eNOS) and inducible (iNOS) isof.....

Read abstract  Full text PDF

Treatment of autoimunne ovarian damage in adolescent girls.

Mlcochová H, Horejsí J, Martinek J, Vetesníková-Koubová R, Halaska M.

Clinical Trial 2005; 26(2): 131-135 PubMed PMID: 15855884  Keywords:  Adolescent, Adult, Autoantibodies:analysis, Drug Combinations, Estradiol:therapeutic use, Estriol:therapeutic use, Female, Germ Cells:immunology, Hormone Replacement Therapy, Humans, Medroxyprogesterone Acetate:therapeutic use, Menstruation Disturbances:c.    Citation

INTRODUCTION: To investigate levels of antiovarian autoantibodies in girls and young women with disturbances of menstrual cycle before and.....

Read abstract  Full text PDF

Serum levels of growth factors HGF (Hepatocyte Growth Factor), TGFbeta1 (transforming growth factor beta1) and IGF-I (Insulin Like Growth Factor I) in parathyroid tumors.

Astl J, Veselý D, Matucha P, Martínek J, Kucera T, Lastuvka P, Betka J, Sterzl I.

Clinical Trial 2004; 25(5): 356-360 PubMed PMID: 15580170  Keywords:  Adenoma:metabolism, Cytokines:blood, Hepatocyte Growth Factor:blood, Humans, Hyperplasia, Insulin-Like Growth Factor I:analysis, Parathyroid Glands:metabolism, Parathyroid Neoplasms:metabolism, Reference Values, Transforming Growth Factor beta:blood,.    Citation

INTRODUCTION: HGF (Hepatocyte Growth Factor), TGFbeta1 (Transforming Growth Factor beta1) and IGF-I (Insulin Like Growth Factor I) are cyt.....

Read abstract  Full text PDF

Anticipated academic examinations induce distinct cortisol responses in adolescent pupils.

Martinek L, Oberascher-Holzinger K, Weishuhn S, Klimesch W, Kerschbaum H.

Journal Article 2003; 24(6): 449-453 PubMed PMID: 15073574  Keywords:  Adolescent, Adult, Educational Measurement, Exploratory Behavior, Female, Humans, Hydrocortisone:metabolism, Male, Psychometrics, Saliva:metabolism, Stress, Psychological:diagnosis, Students:psychology,.    Citation

OBJECTIVES: Although it is widely accepted that academic examinations are accompanied by a cortisol increase, some recent studies reported.....

Read abstract  Full text PDF