Matal J, Matuskova Z, Tunkova A, Anzenbacherova E, Anzenbacher P.
Journal Article 2009; 30(Suppl 1): 36-40 PubMed PMID: 20027142 Keywords: Animals, Cytochrome P-450 CYP1A2:metabolism, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2E1:metabolism, Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System:metabolism, Humans, Indoles:metabol. CitationOBJECTIVES: To study the contribution of individual purified porcine CYP1A2, 2E1 and 2A19 enzymes to the biotransformation of skatole.
Matal J, Matuskova Z, Tunkova A, Anzenbacherova E, Anzenbacher P. Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system. Neuro Endocrinol Lett. 2009 Jan; 30(Suppl 1): 36-40
Matal J, Jancova P, Siller M, Masek V, Anzenbacherova E, Anzenbacher P.
Comparative Study 2008; 29(5): 738-743 PubMed PMID: 18987594 Keywords: Animals, Dogs, Glucuronides:metabolism, Glucuronosyltransferase:metabolism, Haplorhini, Humans, Kinetics, Microsomes, Liver:enzymology, Protective Agents:metabolism, Rats, Silymarin:metabolism, Species Specificity, Swine,. CitationOBJECTIVES: The study of interspecies differences in glucuronidation processes in the man, monkey, pig, dog and rat using liver microsomal.....
Matal J, Jancova P, Siller M, Masek V, Anzenbacherova E, Anzenbacher P. Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat. Neuro Endocrinol Lett. 2008 Oct; 29(5): 738-743
Matal J, Orság J, Nekvindová J, Anzenbacherová E, Veinlichová A, Anzenbacher P, Zídek Z, Holý A.
Journal Article 2006; 27(Suppl 2): 27-30 PubMed PMID: 17159773 Keywords: Adenine:analogs & derivatives, Bacteria:ultrastructure, Cell Membrane:metabolism, Cytochrome P-450 Enzyme System:genetics, Drug Interactions, Humans, Liver:drug effects, Metabolic Detoxication, Phase I, Models, Biological, NADPH-Ferrihemoprotein Reductase. CitationOBJECTIVES: To determine a possible influence of acyclic nucleoside phosphonates on FMO3 and CYP activity at molecular level in vitro.
Matal J, Orság J, Nekvindová J, Anzenbacherová E, Veinlichová A, Anzenbacher P, Zídek Z, Holý A. Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3. Neuro Endocrinol Lett. 2006 Dec; 27(Suppl 2): 27-30