Melkersson K, Lewitt M, Hall K.
Comparative Study 2015; 36(5): 465-480 PubMed PMID: 26707048 Keywords: Adult, Amino Acids:blood, Antipsychotic Agents:therapeutic use, Chromatography, Ion Exchange, Clopenthixol:therapeutic use, Clozapine:therapeutic use, Cohort Studies, Female, Glutamic Acid:blood, Haloperidol:therapeutic use, Humans, Insulin Resistance, Ma. CitationRATIONALE: The effect of long-term treatment with the atypical antipsychotic clozapine on the serum amino acid profile in schizophrenia pa.....
Melkersson K, Lewitt M, Hall K. Higher serum concentrations of tyrosine and glutamate in schizophrenia patients treated with clozapine, compared to in those treated with conventional antipsychotics. Neuro Endocrinol Lett. 2015 Jan; 36(5): 465-480
: This report deals with a female patient with schizophrenia who was found to have a mutation in the insulin receptor substrate-4 gene tha.....
Melkersson K. Case report of a patient with schizophrenia and a mutation in the insulin receptor substrate-4 gene. Neuro Endocrinol Lett. 2013 Jan; 34(3): 173-176
OBJECTIVES: This study was undertaken to examine if patients exhibit more pronounced metabolic abnormalities after 8-year treatment with c.....
Feng S, Melkersson K. Metabolic parameters and long-term antipsychotic treatment: a comparison between patients treated with clozapine or olanzapine. Neuro Endocrinol Lett. 2012 Jan; 33(5): 493-498
OBJECTIVES: Since there are clear indications that schizophrenia is a systemic disorder, we sought for a common molecular basis for schizo.....
Melkersson K, Persson B. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene. Neuro Endocrinol Lett. 2012 Jan; 33(3): 321-330
OBJECTIVES: The insulin receptor substrate-4 (IRS-4) protein is highly expressed in the hypothalamus that plays a main role in the regulat.....
Melkersson K, Persson B. Association between body mass index and insulin receptor substrate-4 (IRS-4) gene polymorphisms in patients with schizophrenia. Neuro Endocrinol Lett. 2011 Jan; 32(5): 634-640
Melkersson K, Berinder K, Hulting A.
Comparative Study 2011; 32(4): 428-436 PubMed PMID: 21876517 Keywords: Adult, Anthropometry, Antipsychotic Agents:adverse effects, Benzodiazepines:adverse effects, Blood Glucose:drug effects, Clozapine:adverse effects, Female, Glucose Intolerance:chemically induced, Humans, Hyperprolactinemia:chemically induced, Insulin Resi. CitationOBJECTIVES: This study consisting of two subprojects was undertaken to evaluate the effects of hyperprolactinemia on cardiovascular diseas.....
Melkersson K, Berinder K, Hulting A. Effect of antipsychotic-induced hyperprolactinemia on anthropometric measures, insulin sensitivity and lipid profile in patients with schizophrenia or related psychoses. Neuro Endocrinol Lett. 2011 Jan; 32(4): 428-436