Chronic unpredictable mild stress paradigm in male Wistar rats: effect on anxiety- and depressive-like behavior. Koprdova R, Bögi E, Belovičová K, Sedláčková N, Okuliarová M, Ujházy E, Mach M. Journal Article 2016; 37(Suppl 1): 103-110 PubMed PMID: 28263537 Keywords: Animals, Anxiety:physiopathology, Behavior, Animal:physiology, Corticosterone:blood, Depression:physiopathology, Disease Models, Animal, Male, Rats, Rats, Wistar, Stress, Psychological:blood,. Citation OBJECTIVES: There are several models of depression. Chronic unpredictable mild stress (CMS) appears to have the greatest validity..... Read abstract Full text PDF