Mathematical modelling the systemic regulation of blood glucose: 'a top-down' systems biology approach.

Journal Article 2011; 32(4): 371-379 PubMed PMID: 21876496 Keywords: Autonomic Nervous System:physiology, Blood Glucose:metabolism, Diabetes Mellitus:physiopathology, Homeostasis:physiology, Humans, Models, Biological, Neurosecretory Systems:physiology,.

: The objective of this article is to review the mechanisms which the body uses to regulate its function. The author considers, in particu.....

Diabetes mellitus decreases the expression of calcitonin-gene related peptide, gamma-amino butyric acid and glutamic acid decarboxylase in human pancreatic islet cells.

Journal Article 2009; 30(4): 506-510 PubMed PMID: 20010500 Keywords: Calcitonin Gene-Related Peptide:metabolism, Diabetes Mellitus, Type 2:metabolism, Fluorescent Antibody Technique, Glucagon:metabolism, Glutamate Decarboxylase:metabolism, Humans, Insulin:metabolism, Insulin-Secreting Cells:cytology, Pancreatectomy, Pancre.

OBJECTIVES: The pattern of distribution of calcitonin-gene related peptide (CGRP), a neuropeptide, gamma-aminobutyric acid (GABA), a neuro.....

Comparative Study 2007; 28(4): 484-488 PubMed PMID: 17693962 Keywords: Aging:physiology, Albinism:genetics, Animals, Antithyroid Agents:adverse effects, Bone Density:drug effects, Bone Development:drug effects, Carbimazole:adverse effects, Hormone Replacement Therapy:methods, Hypothyroidism:chemically induced, Rats, Rats, Mu.

: To evaluate the effect of carbimazole induced hypothyroidism and thyroxine replacement, on the growth of long bones of albino rats of di.....

Journal Article 2007; 28(4): 489-495 PubMed PMID: 17693961 Keywords: Animals, Cell Count, Circadian Rhythm:physiology, Corticosterone:blood, Immune System:physiology, Macrophages:pathology, Male, Melatonin:blood, Microspheres, Peritoneal Cavity:cytology, Phagocytosis:physiology, Physical Conditioning, Animal:physiology, Ra.

: Corticosterone is thought to be the main glucocorticoid secreted in response to stressful exercise, while melatonin buffers the adverse .....

Journal Article 2007; 28(4): 360-366 PubMed PMID: 17693960 Keywords: Bottle Feeding, Chronotherapy, Circadian Rhythm:physiology, Dietary Carbohydrates:administration & dosage, Double-Blind Method, Feeding Behavior:physiology, Humans, Infant, Infant Formula:administration & dosage, Infant, Newborn, Prospective Studies, Slee.

UNLABELLED: Some 30% of pre-weaning infants present problems of sleep during the night, especially those who are bottle-fed. The solution .....

Clinical Trial 2005; 26(6): 657-661 PubMed PMID: 16380706 Keywords: Bottle Feeding, Breast Feeding, Circadian Rhythm:physiology, Female, Humans, Infant, Infant, Newborn, Male, Melatonin:analogs & derivatives, Milk, Human:metabolism, Reference Values, Sleep:physiology, Statistics, Nonparametric, Tryptophan:metabolism,.

INTRODUCTION: The hormone melatonin regulates the sleep and this pineal hormone is synthesized in the organism from the amino acid tryptop.....