Articles by author - Andrea Sevcovicova

Dual activities of emodin--DNA protectivity vs mutagenicity.

Sevcovicova A, Bodnarova K, Loderer D, Imreova P, Galova E, Miadokova E.

Journal Article 2014; 35(Suppl 2): 149-154 PubMed PMID: 25638379  Keywords:  Antioxidants:pharmacology, DNA Damage:drug effects, Emodin:pharmacology, Humans, Mutagenicity Tests, Mutagens:pharmacology, Mutation:drug effects,.    Citation

OBJECTIVES: Emodin is a bioactive anthraquinone that has diverse biological effects. It is also known as a biosynthetic precursor.....

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Cytotoxic and genotoxic effect of methanolic flower extract from Gentiana asclepiadea on COS 1 cells.

Hudecova A, Hasplova K, Miadokova E, Magdolenova Z, Rinna A, Galova E, Sevcovicova A, Vaculcikova D, Gregan F, Dusinska M.

Journal Article 2010; 31(Suppl 2): 21-25 PubMed PMID: 21187836  Keywords:  Animals, Apoptosis:drug effects, COS Cells, Cercopithecus aethiops, Cytotoxins:pharmacology, DNA Damage:drug effects, Dose-Response Relationship, Drug, Flowers, Gentiana, Kidney:cytology, Models, Animal, Mutagens:pharmacology, Plant Extracts:pharmacology,.    Citation

OBJECTIVE: The purpose of this study was to assess whether a methanol extract isolated from the flower of Gentiana asclepiadea had potenti.....

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Bisphenol A as an environmental pollutant with dual genotoxic and DNA-protective effects.

Durovcova I, Spackova J, Puskar M, Galova E, Sevcovicova A.

Journal Article 2018; 39(4): 294-298 PubMed PMID: 30531698  Keywords:  Benzhydryl Compounds:toxicity, Comet Assay, DNA:drug effects, DNA Breaks, Double-Stranded:drug effects, DNA Damage:drug effects, Endocrine Disruptors:toxicity, Environmental Pollutants:toxicity, Estrogens, Non-Steroidal:toxicity, Free Radical Scavengers:t.    Citation

OBJECTIVES: Bisphenol A (BPA) is an endocrine disruptor which has been shown to be a harmful compound for living organisms. It is the main.....

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